DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AsnS and ASN1

DIOPT Version :9

Sequence 1:	NP_996132.1	Gene:	AsnS / 2768965	FlyBaseID:	FBgn0270926	Length:	558	Species:	Drosophila melanogaster
Sequence 2:	NP_190318.1	Gene:	ASN1 / 823888	AraportID:	AT3G47340	Length:	584	Species:	Arabidopsis thaliana

Alignment Length:	579	Identity:	259/579 - (44%)
Similarity:	341/579 - (58%)	Gaps:	55/579 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCGIFAIF--SRDGEPIPTQILHGSKHSLRELAYRQSGKHRHRGPDSTGVYVNSLEGVAMIHERL 63
            ||||.|:.  |.|.:....::|        ||:.|.    ||||||.:|:|.|....:|  |:||
plant     1 MCGILAVLGCSDDSQAKRVRVL--------ELSRRL----RHRGPDWSGLYQNGDNYLA--HQRL 51

  Fly    64 RIIGVEMGDQPFVSEDGNLILVANGEIYNYLELSAEIAKKRGSYNPMSDCHVILELYQDYGKDLL 128
            .:|....||||..:||..:::..||||||:.||...:  |...:...|||.||..||::||.|.:
plant    52 AVIDPASGDQPLFNEDKTIVVTVNGEIYNHEELRKRL--KNHKFRTGSDCEVIAHLYEEYGVDFV 114

  Fly   129 QYITGMFAFALYDRKTKEVLLARDPFGIIPMYVGEDASGNLWVASEMKCLVDTCSKVETFTPGEA 193
            ..:.|:|:|.|.|.:....::|||..|:..:|:|....|::|::||||.|.|.|...|||.||..
plant   115 DMLDGIFSFVLLDTRDNSFMVARDAIGVTSLYIGWGLDGSVWISSEMKGLNDDCEHFETFPPGHF 179

  Fly   194 RFGKVGDFKTCWQFQQSWIKE-VPTQTCELSLLRANLEFAVRSHLQCDVQMGALLSGGVDSSLIA 257
            ...|:|.||. | :...|..| ||:...|...:|...|.||...|..||..|.|||||:||||:|
plant   180 YSSKLGGFKQ-W-YNPPWFNESVPSTPYEPLAIRRAFENAVIKRLMTDVPFGVLLSGGLDSSLVA 242

  Fly   258 SI------ATKIMRERDPNFRLKTFSVGLRDAPDFQAARSVAKYIDSDHKEIIFEIDEALDGIRD 316
            ||      .||..::..|  :|.:|.|||..:||.:|.:.||:|:.:.|.|..|.:.:.:|.|.|
plant   243 SITARHLAGTKAAKQWGP--QLHSFCVGLEGSPDLKAGKEVAEYLGTVHHEFHFSVQDGIDAIED 305

  Fly   317 IIYHLETYDVTTVRCSLPMLLLARYIKSTGIKMILSGEGADEIFGGYLYFHKAPSYNDFHEELVK 381
            :|||:|||||||:|.|.||.|::|.|||.|:||:||||||||||||||||||||:..:||:|..:
plant   306 VIYHVETYDVTTIRASTPMFLMSRKIKSLGVKMVLSGEGADEIFGGYLYFHKAPNKKEFHQETCR 370

  Fly   382 RVRQLHLSDCLRANKVAMAKGVELRVPFLDTGFVNHVMQIRPEDKIPGPLNKFGEVQQKRLEKYV 446
            :::.||..|||||||...|.|:|.||||||..|:|..|.:.||.|:..|       ::.|:||:|
plant   371 KIKALHKYDCLRANKSTSAFGLEARVPFLDKDFINTAMSLDPESKMIKP-------EEGRIEKWV 428

  Fly   447 LRAAFADN---YLPDEVLWRQKEQFSDGVGYDWIDSIRRVATSHVSDQEFSAAALRFPFNTPTTK 508
            ||.||.|.   |||..:|:||||||||||||.|||.::..|..:|:|:..|.|...||.|||.||
plant   429 LRRAFDDEERPYLPKHILYRQKEQFSDGVGYSWIDGLKDHAAQNVNDKMMSNAGHIFPHNTPNTK 493

  Fly   509 EAFYYRCIFAEQFPGESAARTV-------------VRWVPRLDWGCPEDPSGRAQ-AVH 553
            ||:|||.||...||..||..||             |.|  ...|....||||||. .||
plant   494 EAYYYRMIFERFFPQNSARLTVPGGATVACSTAKAVEW--DASWSNNMDPSGRAAIGVH 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AsnS	NP_996132.1	asnB	1..554	CDD:236513	259/579 (45%)
		AsnB	2..>182	CDD:238364	68/181 (38%)
		Asn_synthase	225..528	CDD:279122	161/311 (52%)
ASN1	NP_190318.1	PLN02549	1..578	CDD:178164	259/579 (45%)
		AsnB	2..192	CDD:238364	79/207 (38%)
		Asn_synthase	209..511	CDD:279122	159/310 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	163	1.000	Domainoid score	I1237
eggNOG	1	0.900	-	-		E1_COG0367
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H49128
Inparanoid	1	1.050	452	1.000	Inparanoid score	I384
OMA	1	1.010	-	-		QHG62355
OrthoDB	1	1.010	-	-		D782607at2759
OrthoFinder	1	1.000	-	-		FOG0001900
OrthoInspector	1	1.000	-	-		otm3380
orthoMCL	1	0.900	-	-		OOG6_100710
Panther	1	1.100	-	-	O	PTHR11772
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1254
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840