Protein Alignment AsnS and ASNSD1

DIOPT Version :9

• Sequence 1: NP_996132.1
• Gene: AsnS / 2768965
• FlyBaseID: FBgn0270926
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001340426.1
• Gene: ASNSD1 / 54529
• HGNCID: 24910
• Length: 643
• Species: Homo sapiens
• Alignment Length: 641
• Identity: 122/641 - (19%)
• Similarity: 211/641 - (32%)
• Gaps: 245/641 - (38%)

  Fly     1 MCGIFAIFSRDGEPIPTQILHGSKHSLRELAYRQSGKHRHRGPDSTGVYVNS------LEGVAMI 59
            ||||....:...|       |.|:....:|.|..    :.|||:|:...:.|      |....::
Human     1 MCGICCSVNFSAE-------HFSQDLKEDLLYNL----KQRGPNSSKQLLKSDVNYQCLFSAHVL 54

  Fly    60 HERLRIIGVEMGDQPFVSEDGNLILVANGEIYNYLELSAEIAKKRGSYNPMSDC---HVILELYQ 121
            |.|    || :..||...|.||:.| .||||::.:::.||....:..:|.:|.|   ..||.|:.
Human    55 HLR----GV-LTTQPVEDERGNVFL-WNGEIFSGIKVEAEENDTQILFNYLSSCKNESEILSLFS 113

  Fly   122 DYGKDLLQYITGMFAFALYDRKTKEVLLARDPFGIIPMY--------------VGEDASG--NLW 170
            :        :.|.::|..|...:..:...||.||...:.              ||...||  |.|
Human   114 E--------VQGPWSFIYYQASSHYLWFGRDFFGRRSLLWHFSNLGKSFCLSSVGTQTSGLANQW 170

  Fly   171 ----------------------------------------------------------VASEMKC 177
                                                                      ||:|.|.
Human   171 QEVPASGLFRIDLKSTVISGCIILQLYPWKYISRENIIEENVNSLSQISADLPAFVSVVANEAKL 235

  Fly   178 LVDT-----------------CSKVETFTPGEARFGKVGDFKTCWQFQQSWI-----KEVPTQTC 220
            .::.                 ||.:....|..             :..|.::     |||..|..
Human   236 YLEKPVVPLNMMLPQAALETHCSNISNVPPTR-------------EILQVFLTDVHMKEVIQQFI 287

  Fly   221 ELSLLRANLEFAVRSHLQC------------------DVQMGALLSGGVDSSLIASIATKIMRER 267
            ::      |..||:..:.|                  ...:..|.|||:||.:||::|.:.:...
Human   288 DV------LSVAVKKRVLCLPRDENLTANEVLKTCDRKANVAILFSGGIDSMVIATLADRHIPLD 346

  Fly   268 DPNFRL--------KTFSVGLR----------DAPDFQAARSV-AKYIDSDHKEI---------- 303
            :|...|        ||......          :.|..:.::.| |...||.:|.:
Human   347 EPIDLLNVAFIAEEKTMPTTFNREGNKQKNKCEIPSEEFSKDVAAAAADSPNKHVSVPDRITGRA 411

  Fly   304 ---------------IFEIDEALDGIRDI----IYH----LETYDVTTVRCS-------LPMLLL 338
                           ..||:.:::.::.:    |.|    |:|....::.|:       :..|:.
Human   412 GLKELQAVSPSRIWNFVEINVSMEELQKLRRTRICHLIRPLDTVLDDSIGCAVWFASRGIGWLVA 476

  Fly   339 ARYIKS--TGIKMILSGEGADEIFGGYLYFH---KAPSYNDFHEELVKRVRQLHLSDCLRANKVA 398
            ...:||  :..|::|:|.||||...||....   ::......::|::..:.::...:..|.::|.
Human   477 QEGVKSYQSNAKVVLTGIGADEQLAGYSRHRVRFQSHGLEGLNKEIMMELGRISSRNLGRDDRVI 541

  Fly   399 MAKGVELRVPFLDTGFVNHVMQIRPEDK----IPGPLNKFGEVQQKRLEKYVLRAA 450
            ...|.|.|.||||...|:.:..:...:|    :|..:.          ||.:||.|
Human   542 GDHGKEARFPFLDENVVSFLNSLPIWEKANLTLPRGIG----------EKLLLRLA 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AsnS	NP_996132.1	asnB	1..554	CDD:236513	122/641 (19%)
		AsnB	2..>182	CDD:238364	53/279 (19%)
		Asn_synthase	225..528	CDD:279122	60/312 (19%)
ASNSD1	NP_001340426.1	Gn_AT_II_novel	1..179	CDD:239735	50/202 (25%)
		Asn_Synthase_B_C	322..607	CDD:238949	56/276 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0367
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810