Protein Alignment CG7369 and rasgef1bb

DIOPT Version :10

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001003479.1
• Gene: rasgef1bb / 445085
• ZFINID: ZDB-GENE-040801-220
• Length: 475
• Species: Danio rerio
• Alignment Length: 622
• Identity: 233/622 - (37%)
• Similarity: 327/622 - (52%)
• Gaps: 162/622 - (26%)

  Fly    48 TTSITHKTLPDLKTQRSNSACHAHESLSALRRIALLEKPPEKLLSYGAAQSRILGQEAREDFLVY 112
            ||..:.|..|.     :.|:.|:|            .:|.|:  :||.              |.|
Zfish     4 TTPYSSKFNPS-----AYSSSHSH------------RQPVEE--NYGG--------------LHY 35

  Fly   113 SEGRLHSGPLQSLIAHMVPTHEYYPDEGFIFAFLLSARLFVRPHELLAQISQTWEHQQQDVGTGG 177
            .:.:|.||.|::||..:|||.:||||..:||.||||:|||:.|.||::::..        :|...
Zfish    36 RDNKLVSGSLEALIQLLVPTVDYYPDRSYIFTFLLSSRLFLNPFELMSRVCY--------LGVDH 92

  Fly   178 DVVDDAGQGPGRTMMVSINSASPLTQRKGSAAAASHSSELEPRLQQRTNTQRSAQHCIRLLSEWI 242
            ..|.|                 |...:|       ...::.|::             ::||:||.
Zfish    93 HRVGD-----------------PQMDKK-------RIRDIAPKI-------------VQLLTEWT 120

  Fly   243 EIFPYDFRDERLMQQVRILARKCVYIDNSLGKQVSRILQLLVSRLTTLEQYEEFLQTISSEEA-- 305
            |.|||||||||:|:.::.:..:..:.|....:.:.|::|.|:.:||||.||||.|.|.|:..|
Zfish   121 ETFPYDFRDERMMRSLKEMTHRLAFGDELSRRAMQRLIQRLLRKLTTLGQYEESLATTSAAAAID 185

  Fly   306 -----QSQQQQHHHHHGHHNHLHNAFQTFLGSSSHANGASGGGGSASGTSNSSSSGHTSSASTSN 365
                 :|:||
Zfish   186 RPVALKSKQQ------------------------------------------------------- 195

  Fly   366 SISTTPQPDDVFGIMDMCPSCAHLAHQLTAIELERLSHIGPEEFVQAFAKDYQQQAKDGSREANN 430
                ..:.||.  ::::|......|.|||.||:||||:|||||||:|||:         .|.::|
Zfish   196 ----LVRRDDC--VLNLCDDPFIFAQQLTHIEMERLSYIGPEEFVRAFAQ---------KRPSDN 245

  Fly   431 SKCSGGGGGSLNDMKKTRNLESYVQWFNRLSYLTASEIVKYPKKKQRVRIIEYWIETARECFNIG 495
            .|       |....:|..|||:||:||||||||||:||....|||.|.|::|::|:.|:||||||
Zfish   246 HK-------SFFSKRKASNLEAYVEWFNRLSYLTATEICMPVKKKHRARVLEFFIDVAQECFNIG 303

  Fly   496 NFNSLMAIIAGLNLAPIGRLKKTWAKVQSAKFSVLEHQMDPTSNFNSYRSTLKAAMWRSEGATEE 560
            |||||||||.|:|:.|:.||||||.||.:.||.:|.|||||:|||.|||:.|:.|..||..|...
Zfish   304 NFNSLMAIITGMNMNPVSRLKKTWGKVNTDKFDILVHQMDPSSNFYSYRTALRGATQRSSTAHTS 368

  Fly   561 RERIIIPFFSLFVKDLYFLNEGCSNRLPNNHINFEKCSQLAKQVMEFNEWKKVNCPFERLPNVIA 625
            :|.|:|||||||:||:|||||||:|||.|.||||||..:|||||.||..|::|.|||||....:.
Zfish   369 QEMIVIPFFSLFIKDIYFLNEGCANRLSNGHINFEKFWELAKQVSEFLSWRQVICPFERDRKTLQ 433

  Fly   626 YLQNSAVLNENTLSMASFECEPPENTEEKDRYRTVKA 662
            ||.::.|.:|:.|.:||:|.|.|||..|:|..|::::
Zfish   434 YLISAPVFSEDELQLASYESEGPENNLERDTRRSLRS 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	REM	122..284	CDD:100121	46/161 (29%)
		RasGEF	388..597	CDD:459872	122/208 (59%)
rasgef1bb	NP_001003479.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		7/37 (19%)
		REM	44..168	CDD:100121	49/168 (29%)
		RasGEF	213..406	CDD:459872	123/208 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	452..475		8/19 (42%)