Protein Alignment CG7369 and rasgef1bb

DIOPT Version :9

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001003479.1
• Gene: rasgef1bb / 445085
• ZFINID: ZDB-GENE-040801-220
• Length: 475
• Species: Danio rerio
• Alignment Length: 622
• Identity: 233/622 - (37%)
• Similarity: 327/622 - (52%)
• Gaps: 162/622 - (26%)

  Fly    48 TTSITHKTLPDLKTQRSNSACHAHESLSALRRIALLEKPPEKLLSYGAAQSRILGQEAREDFLVY 112
            ||..:.|..|.     :.|:.|:|            .:|.|:  :||.              |.|
Zfish     4 TTPYSSKFNPS-----AYSSSHSH------------RQPVEE--NYGG--------------LHY 35

  Fly   113 SEGRLHSGPLQSLIAHMVPTHEYYPDEGFIFAFLLSARLFVRPHELLAQISQTWEHQQQDVGTGG 177
            .:.:|.||.|::||..:|||.:||||..:||.||||:|||:.|.||::::..        :|...
Zfish    36 RDNKLVSGSLEALIQLLVPTVDYYPDRSYIFTFLLSSRLFLNPFELMSRVCY--------LGVDH 92

  Fly   178 DVVDDAGQGPGRTMMVSINSASPLTQRKGSAAAASHSSELEPRLQQRTNTQRSAQHCIRLLSEWI 242
            ..|.|                 |...:|       ...::.|::             ::||:||.
Zfish    93 HRVGD-----------------PQMDKK-------RIRDIAPKI-------------VQLLTEWT 120

  Fly   243 EIFPYDFRDERLMQQVRILARKCVYIDNSLGKQVSRILQLLVSRLTTLEQYEEFLQTISSEEA-- 305
            |.|||||||||:|:.::.:..:..:.|....:.:.|::|.|:.:||||.||||.|.|.|:..|
Zfish   121 ETFPYDFRDERMMRSLKEMTHRLAFGDELSRRAMQRLIQRLLRKLTTLGQYEESLATTSAAAAID 185

  Fly   306 -----QSQQQQHHHHHGHHNHLHNAFQTFLGSSSHANGASGGGGSASGTSNSSSSGHTSSASTSN 365
                 :|:||
Zfish   186 RPVALKSKQQ------------------------------------------------------- 195

  Fly   366 SISTTPQPDDVFGIMDMCPSCAHLAHQLTAIELERLSHIGPEEFVQAFAKDYQQQAKDGSREANN 430
                ..:.||.  ::::|......|.|||.||:||||:|||||||:|||:         .|.::|
Zfish   196 ----LVRRDDC--VLNLCDDPFIFAQQLTHIEMERLSYIGPEEFVRAFAQ---------KRPSDN 245

  Fly   431 SKCSGGGGGSLNDMKKTRNLESYVQWFNRLSYLTASEIVKYPKKKQRVRIIEYWIETARECFNIG 495
            .|       |....:|..|||:||:||||||||||:||....|||.|.|::|::|:.|:||||||
Zfish   246 HK-------SFFSKRKASNLEAYVEWFNRLSYLTATEICMPVKKKHRARVLEFFIDVAQECFNIG 303

  Fly   496 NFNSLMAIIAGLNLAPIGRLKKTWAKVQSAKFSVLEHQMDPTSNFNSYRSTLKAAMWRSEGATEE 560
            |||||||||.|:|:.|:.||||||.||.:.||.:|.|||||:|||.|||:.|:.|..||..|...
Zfish   304 NFNSLMAIITGMNMNPVSRLKKTWGKVNTDKFDILVHQMDPSSNFYSYRTALRGATQRSSTAHTS 368

  Fly   561 RERIIIPFFSLFVKDLYFLNEGCSNRLPNNHINFEKCSQLAKQVMEFNEWKKVNCPFERLPNVIA 625
            :|.|:|||||||:||:|||||||:|||.|.||||||..:|||||.||..|::|.|||||....:.
Zfish   369 QEMIVIPFFSLFIKDIYFLNEGCANRLSNGHINFEKFWELAKQVSEFLSWRQVICPFERDRKTLQ 433

  Fly   626 YLQNSAVLNENTLSMASFECEPPENTEEKDRYRTVKA 662
            ||.::.|.:|:.|.:||:|.|.|||..|:|..|::::
Zfish   434 YLISAPVFSEDELQLASYESEGPENNLERDTRRSLRS 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	RasGEF_N	116..261	CDD:279012	46/144 (32%)
		RasGEF	388..649	CDD:214539	146/260 (56%)
rasgef1bb	NP_001003479.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25		7/37 (19%)
		REM	44..168	CDD:100121	49/168 (29%)
		RasGEF	213..406	CDD:279011	123/208 (59%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	452..475		8/19 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593567
Domainoid	1	1.000	260	1.000	Domainoid score	I1935
eggNOG	1	0.900	-	-		E1_KOG3541
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	408	1.000	Inparanoid score	I1856
OMA	1	1.010	-	-		QHG57431
OrthoDB	1	1.010	-	-		D246323at33208
OrthoFinder	1	1.000	-	-		FOG0001827
OrthoInspector	1	1.000	-	-		otm25572
orthoMCL	1	0.900	-	-		OOG6_104212
Panther	1	1.100	-	-	O	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1189
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	14	13.770