Protein Alignment CG7369 and Rasgef1c

DIOPT Version :10

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001101743.1
• Gene: Rasgef1c / 360519
• RGDID: 1311549
• Length: 466
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 213/561 - (37%)
• Similarity: 298/561 - (53%)
• Gaps: 126/561 - (22%)

  Fly   102 GQEAREDFLVYSEGRLHSGPLQSLIAHMVPTHEYYPDEGFIFAFLLSARLFVRPHELLAQISQTW 166
            |::|.:..|   :|...|..|::||.|:|||.:|||::.:||.||||:|||:.|.||||::....
  Rat    26 GEQAGQPLL---DGAPSSASLETLIQHLVPTADYYPEKAYIFTFLLSSRLFIEPRELLARVCHLC 87

  Fly   167 EHQQQDVGTGGDVVDDAGQGPGRTMMVSINSASPLTQRKGSAAAASHSSELEPRLQQRTNTQRSA 231
            ..|||                                             |:..:..:...::..
  Rat    88 IEQQQ---------------------------------------------LDKPVLDKARVRKFG 107

  Fly   232 QHCIRLLSEWIEIFPYDFRDERLMQQVRILARKCVYIDNSLGKQVSRILQLLVSRLTTLEQYEEF 296
            ...::||:||.|.||.||.:|..:..:..:..:....|.:.|.::.::||.|..:|.:|.|..|
  Rat   108 AKLLQLLAEWTETFPRDFEEESTIGHLTDVVGRISPCDETYGNRMHQLLQTLHQKLASLGQGPE- 171

  Fly   297 LQTISSEEAQSQQQQHHHHHGHHNHLHNAFQTFLGSSSHANGASGGGGSASGTSNSSSSGHTSSA 361
                                                     |..|.....|..:...:|.|..
  Rat   172 -----------------------------------------GLVGADKPISYRTKPPASIHRE-- 193

  Fly   362 STSNSISTTPQPDDVFGIMDMCPSCAHLAHQLTAIELERLSHIGPEEFVQAFAKDYQQQAKDGSR 426
                             ::.:|.....||.|||.:|||||.|||||||||||.
  Rat   194 -----------------LLGVCSDPYTLAQQLTHVELERLRHIGPEEFVQAFV------------ 229

  Fly   427 EANNSKCSGGGGGSLNDMKKTRNLESYVQWFNRLSYLTASEIVKYPKKKQRVRIIEYWIETAREC 491
               |.....|.....||  ||.|:|:||:|||||.||.|:||....|||||.::||::|:.||||
  Rat   230 ---NKDPLAGTKPRFND--KTNNVEAYVKWFNRLCYLVATEICMPAKKKQRAQVIEFFIDVAREC 289

  Fly   492 FNIGNFNSLMAIIAGLNLAPIGRLKKTWAKVQSAKFSVLEHQMDPTSNFNSYRSTLKAAMWRSEG 556
            |||||||||||||:|:|::|:.|||||||||::|||.:||||||||.||.:||:.|:.|..||..
  Rat   290 FNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFFILEHQMDPTGNFCNYRTALRGAAHRSLT 354

  Fly   557 ATEERERIIIPFFSLFVKDLYFLNEGCSNRLPNNHINFEKCSQLAKQVMEFNEWKKVNCPFERLP 621
            |...||:|:||||||.:||:|||||||:|||||.|:||||..:|||||.||..||:|.||||:.|
  Rat   355 AHSSREKIVIPFFSLLIKDIYFLNEGCANRLPNGHVNFEKFLELAKQVGEFITWKQVECPFEQDP 419

  Fly   622 NVIAYLQNSAVLNENTLSMASFECEPPENTEEKDRYRTVKA 662
            ::..||..:.:.:|:.|.:||:|.|.|||..||:|::::::
  Rat   420 SITHYLYTAPIFSEDGLYLASYESESPENQTEKERWKSLRS 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	REM	122..284	CDD:100121	42/161 (26%)
		RasGEF	388..597	CDD:459872	125/208 (60%)
Rasgef1c	NP_001101743.1	REM	42..163	CDD:100121	43/165 (26%)
		RasGEF	204..395	CDD:459872	125/207 (60%)