Protein Alignment CG7369 and CG34393

DIOPT Version :9

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001285578.1
• Gene: CG34393 / 33534
• FlyBaseID: FBgn0085422
• Length: 691
• Species: Drosophila melanogaster
• Alignment Length: 780
• Identity: 191/780 - (24%)
• Similarity: 273/780 - (35%)
• Gaps: 278/780 - (35%)

  Fly     3 SSNGGLSSATNGRSGSTGSATINLNLKGHERTIVGVPG--------TGASSATTTSITHKTL--- 56
            |||   ||:|:  |.|.....:.|...|.:....|..|        .|..|.....:|.:|.
  Fly    55 SSN---SSSTD--SESADECGLELGESGADSREAGAGGGAGLQVAQGGIFSLDPGHLTAETALLG 114

  Fly    57 PDLKTQRSNSACHAHESLSA------LRRIAL---LEKPP--EKLLSYGAA-------------Q 97
            .:::.:|.:||    |.|||      .:::.|   :...|  |.|:.|...             :
  Fly   115 GNIRYRRRHSA----EQLSAYDLEMGFQQLELGTTISVGPKNEDLVQYDVPKNPHKRSQCDINFE 175

  Fly    98 SRILGQEAREDFLVYSEGRLHSGPLQSLIAHMVPTHEYYPDEGFIFAFLLSARLFVRPHELLAQI 162
            |.:||...    ::|..||:.||||.|||..::|......|:.|:|:||||.|||:||||||
  Fly   176 SSVLGSGG----IMYINGRIVSGPLDSLIETLLPKDVVDLDKEFVFSFLLSCRLFLRPHELL--- 233

  Fly   163 SQTWEHQQQDVGTGGDVVDDAGQGPGRTMMVSINSASPLTQRKGSAAAASHSSELEPRLQQRTNT 227
                          |.::|...:......:||
  Fly   234 --------------GRLLDSVPESECLESLVS--------------------------------- 251

  Fly   228 QRSAQHCIRLLSEWIEIFPYDFRDERLMQQVRILARKCVYIDNS-LGKQVSRILQLLVSRLTTLE 291
                     ||:||...||||:||||:|..|:.:..:|   .|| |...||:.|..|:.|||.||
  Fly   252 ---------LLAEWTMKFPYDYRDERMMSHVKHIVARC---SNSHLEAAVSQTLSALLKRLTDLE 304

  Fly   292 QYEEFLQTISSEEAQSQQQQHHHHHGHHNHLHNAFQTFLGSSSHANGASGGGGSASGTSNSSSSG 356
            ::|..|:                          |.||        |..||
  Fly   305 RHEADLR--------------------------ACQT--------NDKSG--------------- 320

  Fly   357 HTSSASTSNSISTTPQPDDVFGIMDMCPSCAHLAHQLTAIELERLSHIGPEEFVQAFAKDYQQQA 421
                       ..||.         .||:....|..:..:|.:...|||.|||:|..:    ...
  Fly   321 -----------PETPL---------NCPTATQYAQIVCRVEKKLAKHIGGEEFLQCSS----MIL 361

  Fly   422 KDGSREANNSKCSGGGGGSLNDMKKTRNLESYVQWFNRLSYLTASEIVKYPKKKQRVRIIEYWIE 486
            .|..::.:....||...|: .|.|||.|||:|:.|..||.....:||::....:.|.|.:|.|..
  Fly   362 LDKQKKWDQPSTSGAPPGA-QDPKKTCNLETYLDWSARLRLFVCNEILQSVGIEGRSRTVELWSG 425

  Fly   487 TARECFNIGNFNSLMAIIAGLNLAPIGRLKKTWAKV---------------------QSAKFSVL 530
            .|:.|..:||:||..||:..|....|.|||.||:|:                     |....|:.
  Fly   426 VAQYCLLVGNYNSATAILESLESPAIARLKITWSKLQVTCQQLDCMQRHAEGHGHLWQKQAISLN 490

  Fly   531 EHQ-----------------MDPT----------------------------------------- 537
            |.|                 ..||
  Fly   491 EQQEGLKTDKQAPKEPAAQGAAPTQGAVAIAITTSSDSDEKPSTSGRVAGIAGISAATMESAPVP 555

  Fly   538 --SNFNSYRSTLKAAMWRSEGAT-------EERERIIIPFFSLFVKDLYFLNEGCSNRLPNNHIN 593
              |..|...:|..||...:..||       :..:.::||.|:..||......|.|..||.|.|||
  Fly   556 VASGSNVDAATAAAARTSTTAATTPLASSGKPNDWVVIPVFADIVKLALGERENCLQRLANGHIN 620

  Fly   594 FEKCSQLAKQVMEFNE----WKKVNCPFE-RLPNVIAYLQNSAVLNENTLSMASFECEPPENTEE 653
            .....::|..|..|.:    .|....|.. ...:...::|.:..|.|..|.||||:||.|.|.|:
  Fly   621 MAAFDRMAAIVGAFTKHMQAMKAAQAPSSGEYEHFCRHMQQTTKLGEAELMMASFDCEEPNNAEK 685

  Fly   654  653
              Fly   686  685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	RasGEF_N	116..261	CDD:279012	43/144 (30%)
		RasGEF	388..649	CDD:214539	87/353 (25%)
CG34393	NP_001285578.1	REM	196..300	CDD:100121	47/165 (28%)
		RasGEF	334..>473	CDD:279011	46/143 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3541
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3112
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D246323at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.870