Protein Alignment CG7369 and Rasgef1b

DIOPT Version :10

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_665838.1
• Gene: Rasgef1b / 320292
• MGIID: 2443755
• Length: 473
• Species: Mus musculus
• Alignment Length: 586
• Identity: 245/586 - (41%)
• Similarity: 328/586 - (55%)
• Gaps: 128/586 - (21%)

  Fly    84 EKPPEKLLSYGAAQSRILGQEAREDF--LVYSEGRLHSGPLQSLIAHMVPTHEYYPDEGFIFAFL 146
            :.||...:...:..:|.|.|.|.:..  |.|.:..|.||.|::||.|:||..:||||..:||.||
Mouse     3 QTPPFSAMFDSSGYNRNLYQSAEDSCGGLYYHDNNLLSGSLEALIQHLVPNVDYYPDRTYIFTFL 67

  Fly   147 LSARLFVRPHELLAQISQTW-EHQQQDVGTGGDVVDDAGQGPGRTMMVSINSASPLTQRKGSAAA 210
            ||:|||:.|:||:|::.... |||:...|.|     |..|                 .||
Mouse    68 LSSRLFMHPYELMAKVCHLCVEHQRLSEGDG-----DKNQ-----------------MRK----- 105

  Fly   211 ASHSSELEPRLQQRTNTQRSAQHCIRLLSEWIEIFPYDFRDERLMQQVRILA-RKCVYIDNSLGK 274
                  :.|::             ::||:||.|.|||||||||:|:.::.|| |.....:.:..|
Mouse   106 ------IAPKI-------------LQLLTEWTETFPYDFRDERMMRNLKDLAHRMASGEEQTYRK 151

  Fly   275 QVSRILQLLVSRLTTLEQYEEFLQTISSEEAQSQQQQHHHHHGHHNHLHNAFQTFLGSSSHANGA 339
            .|.:::|.|:.:|..|.||||.|..:||
Mouse   152 NVQQMMQCLIRKLAALSQYEEVLAKLSS------------------------------------- 179

  Fly   340 SGGGGSASGTSNSSSSGHTSSASTSNSISTTPQP---DDVFGIMDMCPSCAHLAHQLTAIELERL 401
                               ::......:.|.||.   |    ||.:|.....||.|||.||||||
Mouse   180 -------------------TATDRLTVLKTKPQSIQRD----IMTVCSDPYTLAQQLTHIELERL 221

  Fly   402 SHIGPEEFVQAFAKDYQQQAKDGSREANNSKCSGGGGGSLNDMKKTRNLESYVQWFNRLSYLTAS 466
            ::||||||||||.   |:...|     |:..|       .::.|||||||:||:||||||||.|:
Mouse   222 NYIGPEEFVQAFV---QKDPLD-----NDKSC-------YSERKKTRNLEAYVEWFNRLSYLVAT 271

  Fly   467 EIVKYPKKKQRVRIIEYWIETARECFNIGNFNSLMAIIAGLNLAPIGRLKKTWAKVQSAKFSVLE 531
            ||....|||.|.|:|||:|:.|||||||||||||||||:|:|::|:.|||||||||::|||.:||
Mouse   272 EICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTWAKVKTAKFDILE 336

  Fly   532 HQMDPTSNFNSYRSTLKAAMWRSEGATEERERIIIPFFSLFVKDLYFLNEGCSNRLPNNHINFEK 596
            |||||:|||.:||:.|:.|..||..|...||:|:||||||.:||:|||||||.|||||.|:||||
Mouse   337 HQMDPSSNFYNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCVNRLPNGHVNFEK 401

  Fly   597 CSQLAKQVMEFNEWKKVNCPFERLPNVIAYLQNSAVLNENTLSMASFECEPPENTEEKDRYRTVK 661
            ..:|||||.||..||:|.|||||...|:.||.:..|.:|:.|.:||:|.|.|||..||||:::::
Mouse   402 FWELAKQVSEFMTWKQVECPFERDRKVLQYLLSVPVFSEDALYLASYESEGPENNIEKDRWKSLR 466

  Fly   662 A 662
            :
Mouse   467 S 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	REM	122..284	CDD:100121	54/163 (33%)
		RasGEF	388..597	CDD:459872	130/208 (63%)
Rasgef1b	NP_665838.1	REM	42..167	CDD:100121	56/170 (33%)
		RasGEF	209..403	CDD:459872	131/208 (63%)