Protein Alignment CG7369 and C3G

DIOPT Version :9

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_572350.2
• Gene: C3G / 31618
• FlyBaseID: FBgn0259228
• Length: 1571
• Species: Drosophila melanogaster
• Alignment Length: 688
• Identity: 144/688 - (20%)
• Similarity: 246/688 - (35%)
• Gaps: 239/688 - (34%)

  Fly    12 TNGRSGSTG-----SATINLNLKGHERTIVGVPGTGASSATTTSITHKTLPDLKTQRSNSA---- 67
            |.|.:||||     .||:...|..             :.|:..::.....|.|.:..:.||
  Fly  1026 TLGENGSTGRPDSRMATVCEELND-------------AVASEDAMPEPRSPVLDSNENVSAVDDG 1077

  Fly    68 ----CHAHESLSALRRIA---------------LLEKPPEKLLSYGAAQSRIL------------ 101
                ||:|:..:|...::               :||:..|.     .|:||.|
  Fly  1078 QTFYCHSHQLPAAEMEMSEDASSADNQPITTPQVLEEQEEP-----TAESRPLVAVHESVKPANV 1137

  Fly   102 --GQEA-REDFLV------------YSEGRLHSGP------LQSLIAHMVPTHEYYPDEGFIFAF 145
              .:|| |.|.|:            ..:.|...||      :.:||.|.....: ..|..|..||
  Fly  1138 DEDEEAERADMLINMLEEVNITRYLILKKREEDGPEVKGGYIDALIVHASRVQK-VADNAFCEAF 1201

  Fly   146 LLSARLFVRPHELLAQISQTWEH---QQQDVGTGGDVVDDAGQGPGRTMMVSINSASPLTQRKGS 207
            :.:.|.|::|.:::.:::..:.:   |.||
  Fly  1202 ITTFRTFIQPIDVIEKLTHRYTYFFCQVQD----------------------------------- 1231

  Fly   208 AAAASHSSELEPRLQQRTNTQRSAQHCIRLLSEWIEIFPYDFRDERLMQQVRILARKCVYIDNSL 272
                              |.|::|:....||...:.    |.....|..|:..|..:.||
  Fly  1232 ------------------NKQKAAKETFALLVRVVN----DLTSTDLTSQLLSLLVEFVY----- 1269

  Fly   273 GKQVSRILQLLVSRLTTLEQYEEFLQTISSEEAQSQQQQHHHHHGHHNHLHNAFQTFLGSSSHAN 337
              |:....||.:::|..    .:|::.::..:....       :|           |:|.
  Fly  1270 --QLVCSGQLYLAKLLR----NKFVEKVTLYKEPKV-------YG-----------FVGE----- 1305

  Fly   338 GASGGGGSASGTSNSSSSGHTSSASTSNSISTTPQPDDVFGIMDMCPSCAHLAHQLTAIELERLS 402
              .||.||..|...:.|.|.:.:|...|      ||    .::|:  ....:|.|:|.::.|..:
  Fly  1306 --LGGAGSVGGAGIAGSGGCSGTAGGGN------QP----SLLDL--KSLEIAEQMTLLDAELFT 1356

  Fly   403 HIG-PEEFVQAFAKDYQQQAKDGSREANNSKCSGGGGGSLNDMKKTRNLESYVQWFNRLSYLTAS 466
            .|. ||  |..||||               :|.          :|:.||..:.:.||::||...|
  Fly  1357 KIEIPE--VLLFAKD---------------QCE----------EKSPNLNKFTEHFNKMSYWARS 1394

  Fly   467 EIVKYPKKKQRVRIIEYWIETARECFNIGNFNSLMAIIAGLNLAPIGRLKKTWAK-----VQSAK 526
            :|::....|:|.:.:..:|:..:....:.|:||.:|:::.|:..||.||:  |.|     |:|
  Fly  1395 KILRLQDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALDSGPIRRLE--WQKGITEEVRS-- 1455

  Fly   527 FSVLEHQMDPTSNFNSYRSTLKAAMWRSEGATEERERIIIPFFSLFVKDLYFLNEGCSNRLPNNH 591
            |..|   :|.:|:|.:||..|           .|.....||:..|.::||.|::.|..:.|....
  Fly  1456 FCAL---IDSSSSFRAYRQAL-----------AETNPPCIPYIGLILQDLTFVHVGNQDYLSKGV 1506

  Fly   592 INFEKCSQLAKQVMEFNEWKKVNCPFERLPNVIAYLQN 629
            |||.|..|....:.....:||...||.|...:|.:..|
  Fly  1507 INFSKRWQQYNIIDNMKRFKKCAYPFRRNERIIRFFDN 1544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	RasGEF_N	116..261	CDD:279012	24/153 (16%)
		RasGEF	388..649	CDD:214539	67/248 (27%)
C3G	NP_572350.2	RasGEFN	1170..1306	CDD:214571	34/229 (15%)
		RasGEF	1335..1558	CDD:238087	68/257 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467904
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23113
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940