Protein Alignment CG7369 and efc25

DIOPT Version :9

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_596123.1
• Gene: efc25 / 2540248
• PomBaseID: SPBC336.03
• Length: 987
• Species: Schizosaccharomyces pombe
• Alignment Length: 569
• Identity: 108/569 - (18%)
• Similarity: 210/569 - (36%)
• Gaps: 173/569 - (30%)

  Fly    91 LSYGAAQSRILGQEAREDFLVYSEGRLHSGPLQSLIAHMVPTHEYYPDEGFIFAFLLSARLFVRP 155
            |...:.||.::......:.:|.|:..:..|.|.:|:.::|  ...:.::.|..:|||:.:.|..|
pombe   568 LGRNSLQSILMLDNLLTNKVVQSDNNVKGGTLPALVHYLV--QNVHLNKDFRHSFLLTYKTFTTP 630

  Fly   156 HELLAQISQTWEHQQQDVGTGGDVVDDAGQGPGRTMMVSINSASPLTQRKGSAAAASHSSELEPR 220
            .||.                              |::|.:....|   ..|..|.|..|.|....
pombe   631 QELF------------------------------TLLVILFHELP---PPGLDATAYSSWEKGDN 662

  Fly   221 LQQRTNTQRSAQHCIRLLSEWIEIFPYDFRDER------LMQQVRILARKCVYIDNSLGKQVSRI 279
            ...:.|.      | .:::.|::  .|.|.|.:      |:.::|...|..|.....:|.    :
pombe   663 FVTKKNV------C-TVMNLWVQ--KYFFEDLKARNTLYLISEMRTFLRDHVVPSFHIGS----V 714

  Fly   280 LQLLVSRLTTLEQYEEFLQTISSEEAQSQQQQHHHHHGHHNHLHNAFQTFLGSSSHANGASGGGG 344
            :...:..|.|.|..:...|.:                     |.:...||:
pombe   715 ILSEIDNLWTEEPPDSLTQRL---------------------LSSPMATFI-------------- 744

  Fly   345 SASGTSNSSSSGHTSSASTSNSISTTPQPDDVFGIMDMCPSCAHLAHQLTAIELERLSHIGPEEF 409
                              :.|..:.||:               ..|.|:|.:|.:.|..|...|:
pombe   745 ------------------SLNVYAYTPE---------------EFASQMTLLEFDYLKQIPSREW 776

  Fly   410 VQAFAKDYQQQAKDGSREANNSKCSGGGGGSLNDMKKTRNLESYVQWFNRLSYLTASEIVKYPKK 474
            :      ::......||.|                     :.:|:.:.|..:|...:.|::....
pombe   777 I------FRSWVSRDSRSA---------------------VRNYINFSNCFTYWIINCILEKKNT 814

  Fly   475 KQRVRIIEYWIETARECFNIGNFNSLMAIIAGLNLAPIGRLKKTWAKVQSAK---FSVLEHQMDP 536
            |.|..:|.::|:||.:|.::.||::||:|::.||.|||.||...:..|::..   .|.|...::.
pombe   815 KARTAVISFFIQTAYKCLSLQNFSTLMSIVSALNSAPIYRLHAAYKLVKAEDIICLSGLREIVET 879

  Fly   537 TSNFNSYRSTLKAAMWRSEGATEERERIIIPFFSLFVKDLYFLNEGCSNRLPNN-H-INFEKCSQ 599
            ..||::||:.|:.|           |...:||..:.:.||.|::||..:.|.:: | ::|.|..:
pombe   880 KKNFSTYRALLRKA-----------ELPCVPFLGVILSDLTFIDEGNPDVLDSSPHLLSFNKRHR 933

  Fly   600 LAKQVMEFNEWKKVNCPFERLPNVIAYL--------QNSAVLNENTLSM 640
            ||..|.:...::..:...:...::.:|:        |:.:.|.:.:||:
pombe   934 LADVVADVCRFQSSSYEMQSNTDLQSYILHRCRFVNQDLSYLFDKSLSL 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	RasGEF_N	116..261	CDD:279012	28/150 (19%)
		RasGEF	388..649	CDD:214539	62/266 (23%)
efc25	NP_596123.1	RasGEF_N	593..700	CDD:279012	28/150 (19%)
		RasGEF	755..932	CDD:279011	54/214 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870