Protein Alignment CG7369 and Rasgef1b

DIOPT Version :10

• Sequence 1: NP_649415.2
• Gene: CG7369 / 2768961
• FlyBaseID: FBgn0037188
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_017454918.1
• Gene: Rasgef1b / 100361238
• RGDID: 1562220
• Length: 480
• Species: Rattus norvegicus
• Alignment Length: 598
• Identity: 245/598 - (40%)
• Similarity: 332/598 - (55%)
• Gaps: 130/598 - (21%)

  Fly    69 HAHESLSALRRIALLEKPPEKLLSYGAAQSRILGQEAREDF--LVYSEGRLHSGPLQSLIAHMVP 131
            |:.||:.        :.||...:...:..:|.:.|.:.:..  |.|.:..|.||.|::||.|:||
  Rat     3 HSRESMP--------QTPPFSAMFDSSGYNRNVYQPSEDSCGGLNYHDNNLLSGSLEALIQHLVP 59

  Fly   132 THEYYPDEGFIFAFLLSARLFVRPHELLAQISQTW-EHQQQDVGTGGDVVDDAGQGPGRTMMVSI 195
            ..:||||..:||.||||:|||:.|:||:|::.... |||:...|.|
  Rat    60 NVDYYPDRTYIFTFLLSSRLFMHPYELMAKVCHLCIEHQRLSEGDG------------------- 105

  Fly   196 NSASPLTQRKGSAAAASHSSELEPRLQQRTNTQRSAQHCIRLLSEWIEIFPYDFRDERLMQQVRI 260
                                       .:..|::.|...::||:||.|.|||||||||:|:.::.
  Rat   106 ---------------------------DKNQTRKIAPKILQLLTEWTETFPYDFRDERMMRNLKD 143

  Fly   261 LA-RKCVYIDNSLGKQVSRILQLLVSRLTTLEQYEEFLQTISSEEAQSQQQQHHHHHGHHNHLHN 324
            || |.....:.:..|.|.:::|.|:.:|..|.||||.|..:||
  Rat   144 LAHRMASGEEQTYRKNVQQMMQCLIRKLAALSQYEEVLAKLSS---------------------- 186

  Fly   325 AFQTFLGSSSHANGASGGGGSASGTSNSSSSGHTSSASTSNSISTTPQPDDVFGIMDMCPSCAHL 389
                                       :::...|...:...||    |.|    ||.:|.....|
  Rat   187 ---------------------------TATDRLTVLKAKPQSI----QRD----IMTVCSDPYTL 216

  Fly   390 AHQLTAIELERLSHIGPEEFVQAFAKDYQQQAKDGSREANNSKCSGGGGGSLNDMKKTRNLESYV 454
            |.|||.||||||::||||||||||.   |:...|     |:..|       .::.|||||||:||
  Rat   217 AQQLTHIELERLNYIGPEEFVQAFV---QKDPLD-----NDKNC-------YSERKKTRNLEAYV 266

  Fly   455 QWFNRLSYLTASEIVKYPKKKQRVRIIEYWIETARECFNIGNFNSLMAIIAGLNLAPIGRLKKTW 519
            :||||||||.|:||....|||.|.|:|||:|:.|||||||||||||||||:|:|::|:.||||||
  Rat   267 EWFNRLSYLVATEICMPVKKKHRARMIEYFIDVARECFNIGNFNSLMAIISGMNMSPVSRLKKTW 331

  Fly   520 AKVQSAKFSVLEHQMDPTSNFNSYRSTLKAAMWRSEGATEERERIIIPFFSLFVKDLYFLNEGCS 584
            |||::|||.:|||||||:|||.:||:.|:.|..||..|...||:|:||||||.:||:|||||||.
  Rat   332 AKVKTAKFDILEHQMDPSSNFLNYRTALRGAAQRSLTAHSSREKIVIPFFSLLIKDIYFLNEGCV 396

  Fly   585 NRLPNNHINFEKCSQLAKQVMEFNEWKKVNCPFERLPNVIAYLQNSAVLNENTLSMASFECEPPE 649
            |||||.|:||||..:|||||.||..||:|.|||||...|:.||.:..|.:|:.|.:||:|.|.||
  Rat   397 NRLPNGHVNFEKFWELAKQVSEFMTWKQVECPFERDRKVLQYLLSVPVFSEDALYLASYESEGPE 461

  Fly   650 NTEEKDRYRTVKA 662
            |..||||:::::|
  Rat   462 NNIEKDRWKSLRA 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7369	NP_649415.2	REM	122..284	CDD:100121	51/163 (31%)
		RasGEF	388..597	CDD:459872	130/208 (63%)
Rasgef1b	XP_017454918.1	REM	49..174	CDD:100121	53/170 (31%)
		RasGEF	216..410	CDD:459872	131/208 (63%)