DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12355 and SYM1

DIOPT Version :9

Sequence 1:	NP_001097610.1	Gene:	CG12355 / 2768954	FlyBaseID:	FBgn0040805	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_013352.1	Gene:	SYM1 / 850953	SGDID:	S000004241	Length:	197	Species:	Saccharomyces cerevisiae

Alignment Length:	192	Identity:	50/192 - (26%)
Similarity:	89/192 - (46%)	Gaps:	23/192 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LFHRY-------PFVTNSAIYGSLYVGAEYSQQFASKRWLATASKPEDIDYATIGRYAVMGTAVY 68
            |.|.|       |..||:.:.|:|:...:.|.|..    ..|:...:..||....|..:.|:.::
Yeast     3 LLHLYEASLKRRPKTTNAIMTGALFGIGDVSAQLL----FPTSKVNKGYDYKRTARAVIYGSLIF 63

  Fly    69 APTLYLWYKWLD-----RAFPGTTKVIIVKKLVLDQFVLTPYLLTVFYAGMSIMEG-SADIF-LE 126
            :.....|||.|:     |..|......:|.::.:||....|..|..::..|||||| |.|:. |:
Yeast    64 SFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAFAPLGLPFYFTCMSIMEGRSFDVAKLK 128

  Fly   127 LREKFVPTFMRSCIFWLPAQALNFSLVAPRFRVIYMGICGLIWVNILCW-----TKRQSLPV 183
            ::|::.||.:.:...|...||:|||:|..:.|::.:.:..:.|...|.:     .::..:||
Yeast   129 IKEQWWPTLLTNWAVWPLFQAINFSVVPLQHRLLAVNVVAIFWNTYLSYKNSKVMEKDKVPV 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12355	NP_001097610.1	Mpv17_PMP22	116..178	CDD:282035	20/68 (29%)
SYM1	NP_013352.1	Mpv17_PMP22	115..176	CDD:397992	20/60 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1944
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55228
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.780