DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12355 and ZK470.1

DIOPT Version :9

Sequence 1:	NP_001097610.1	Gene:	CG12355 / 2768954	FlyBaseID:	FBgn0040805	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_508708.3	Gene:	ZK470.1 / 191323	WormBaseID:	WBGene00022744	Length:	180	Species:	Caenorhabditis elegans

Alignment Length:	191	Identity:	56/191 - (29%)
Similarity:	81/191 - (42%)	Gaps:	38/191 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VRNLFHRYPFVTNSAIYGSLYVGAEYSQQFASKRWLATASKPEDI--------------DYATIG 58
            |||...|:..:||        ||...:|       :.||    ||              |:....
Worm     5 VRNFLARHLLLTN--------VGTSCAQ-------IGTA----DIIQQHINGDVDRDGWDWRRTC 50

  Fly    59 RYAVMGTAVYAPTLYLWYKWLD-RAFPGTTKVIIVKKLVLDQFVLTPYLLTVFYAGMSIMEGS-- 120
            |.|.:| .|.||:|:.:|:.|| |.|.|:....::|||..|. ...||...:|....||.||.
Worm    51 RMAAIG-LVMAPSLHCFYRVLDTRKFIGSRNCKVLKKLAWDT-AFIPYFSCIFMTVGSIYEGKSL 113

  Fly   121 ADIFLELREKFVPTFMRSCIFWLPAQALNFSLVAPRFRVIYMGICGLIWVNILCWTKRQSL 181
            :..|.|.|.|....:......|.|||.:||..:.|..||:|:.:..|::..|:.:.|...|
Worm   114 SAAFAEYRRKMWHIWKVDFTLWPPAQLINFYFMPPALRVVYVNLVSLLYNCIMSYIKNNEL 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12355	NP_001097610.1	Mpv17_PMP22	116..178	CDD:282035	19/63 (30%)
ZK470.1	NP_508708.3	Nuc-transf	<27..>54	CDD:294849	6/30 (20%)
ZK470.1	NP_508708.3	Mpv17_PMP22	109..171	CDD:282035	18/61 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1944
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810