Protein Alignment Pura and LOC5667805

DIOPT Version :10

• Sequence 1: NP_996016.2
• Gene: Pura / 2768948
• FlyBaseID: FBgn0035802
• Length: 1904
• Species: Drosophila melanogaster
• Sequence 2: XP_061512102.1
• Gene: LOC5667805 / 5667805
• VectorBaseID: AGAMI1_004950
• Length: 1099
• Species: Anopheles gambiae
• Alignment Length: 950
• Identity: 213/950 - (22%)
• Similarity: 327/950 - (34%)
• Gaps: 316/950 - (33%)

  Fly   990 QPQSSSSSSSGAFLNV-----------DAACKLRKVTL--LFNEVD-RAAQRLEQLTEQRRERLR 1040
            :|..||::||...:.|           |:   |||:::  |.:::: |||:.||:   ....|..
Mosquito    16 EPAESSAASSMEKIEVLPEPARRTRKRDS---LRKISVRHLVSKLETRAAETLER---NFGGRFS 74

  Fly  1041 QLTRQRALEDEISEVTSWMGSDGAENLQKFSQLHWDNESQLRTQEQEFEKYYFI---AMKHLA-K 1101
            ...|:..||||.:...:...|.|.....:      .:.|..||       :|.:   |.|..: :
Mosquito    75 GRVRKGKLEDEATPSATSSSSGGVPVPDQ------PSSSSART-------WYMVPLSAQKSSSNQ 126

  Fly  1102 GRDLHAAALKVSVLSESA---NNLKSALDQFAQKLELAHERYDAAGRLLHLLTQHQRENAAREEL 1163
            ..|..|||..:|:.|..|   ||..::.|...|...:..::..|               ...|..
Mosquito   127 SADCSAAASSLSLSSSMATDDNNSDNSDDTDVQWAVIGRDKISA---------------DTAEFS 176

  Fly  1164 QRLA-EQLGATSLLEKHWPVMRKTHTLPVASSTPAAAAGKRVSYRCSSASRSSFEGGPSSSN-CS 1226
            |||: |:.|           |:||...|......:.    |.|. ||...|.|.   |...: |.
Mosquito   177 QRLSTEEAG-----------MKKTPGTPTVDREDSG----RWSI-CSDFERDSL---PDVDDVCD 222

  Fly  1227 CWRE-------------------------------------------------SRNLEDMDQME- 1241
            .|.|                                                 .|.|...|.::
Mosquito   223 TWNEFIYLRLSEENAKHLNSYSPDFEVTPFDEYYQPAEASNTIISLRFTPYELHRILHGYDLIDL 287

  Fly  1242 EEEEEQDHDCDGGDGEEQQSKIADSGLGVCDNCERNPKLARICSCQSLNEKSHDELLEDECFDRP 1306
            ..::|.|||.|........|..:||..  .|...::|...||       ..|.|.|.|...|
Mosquito   288 SNDDEDDHDDDVQSHTSHSSTDSDSVF--VDAFVQHPTDVRI-------TPSVDSLDEGVAF--- 340

  Fly  1307 SKRYMDIMHSPMEANAHLQCHGSSLELPKLEEL-SCLDPKIQKTLLLIMREMIGTERDYVRSLYY 1370
                   ..||:|:             |:...| :.:|.||.    .::.|::.|||:|:.:|..
Mosquito   341 -------RDSPVES-------------PEPHHLPNDIDIKIS----FLIEELLDTERNYINTLEK 381

  Fly  1371 VIENYIDELLREDIPQPLRGQRNVIFGNIEKIFEFHNSHFLGELERYERNPLKVGAAFLEM--ES 1433
            .|..|||.:..:..|..|.|::..:|||::.|:.||.:.||..|.....:...:..||:..  ..
Mosquito   382 GIATYIDAVFTDQTPPELCGKKYHLFGNLQYIYRFHRNAFLPRLLTAGNDVELIADAFVHFLDND 446

  Fly  1434 KFYLYALYNKNKPKSDTLLSEYGSSFFKPKQMQLQDKLDLASYLLKPVQRMGKYALLLQQLVKAC 1498
            .||.|.||:...|||..|..:: ..||:..|.|..|||.:.|.:|:|:||:.:|.|||..|.|..
Mosquito   447 SFYGYVLYSMYHPKSQRLCEQH-IEFFRQHQQQHGDKLGVKSLILQPIQRLPRYQLLLTSLFKQL 510

  Fly  1499 KGVEGA---------------ALQEIAA---------DVEELQRAEE-------------MVKFQ 1526
            ....||               .||.:..         |:.:.::||:             :|...
Mosquito   511 VKKPGAISRNTQLHKVCVAEKRLQTLIGIMNESVTVNDILQCEKAEDDEVELGFGVPKPAIVLRN 575

  Fly  1527 LRHGNDLLAMDSLRDCD-------VNVKEQG-------------RLLRQNEFLVWQGRGGKKTLR 1571
            ..|.|.:|.:.. :|.:       :|:..||             ||.||     :|||
Mosquito   576 QNHDNQVLFLYP-KDNEHVDHNKPINILHQGKFRSVFPVFINDLRLKRQ-----YQGR------- 627

  Fly  1572 QVFLFEELVLFSKARRFPDHKNLDIYIYKNSIKTSDIGLTAHTGDSATKFEIWFRKRKPDDTWML 1636
             :|:||..|                 ||...:....:....|......:|:  |..|
Mosquito   628 -LFVFERCV-----------------IYTEQLDLKSLTYRGHYTHQEVEFD--FTNR-------- 664

  Fly  1637 QCMSEDIKNAWTEEISKLLWKQAKR-NREVRLAEMSSMGIGSKPCLDIRPSNNQISDR------- 1693
                         :|.||..::.:| ..||:: .:.|.|....|  |:..:...|.||
Mosquito   665 -------------QILKLSSRRHERLEIEVKV-NIQSPGKTHLP--DVMMAIKTIIDRRDQRESF 713

  Fly  1694 ------SIPLAQLNKTPKLRHSEPGKGSMRRPNSLISESSLSSGTSTTSGSS-ISGGSSSGHNDG 1751
                  ...||.|..|...|:|                |..||.:||||.|| :|..||......
Mosquito   714 AFDGAAGEALAMLRDTFSRRNS----------------SFRSSFSSTTSDSSFLSVFSSPAAAAA 762

  Fly  1752 GGRHSLHFGKLPGAHSASS--TNCSATLELINETQALKLA 1789
            ....|...|   .||.|.|  :.|.:...:::..|..:.|
Mosquito   763 AEEDSTAAG---SAHRAGSVLSECGSIETMLHFQQHFERA 799

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pura	NP_996016.2	COG4913	<1020..>1167	CDD:443941	34/154 (22%)
		RhoGEF	1353..1524	CDD:459876	58/209 (28%)
		PH_puratrophin-1	1524..1663	CDD:270062	28/159 (18%)
LOC5667805	XP_061512102.1	None