DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42458 and hnrnpc

DIOPT Version :9

Sequence 1:	NP_996010.2	Gene:	CG42458 / 2768945	FlyBaseID:	FBgn0259935	Length:	711	Species:	Drosophila melanogaster
Sequence 2:	XP_012815605.1	Gene:	hnrnpc / 448664	XenbaseID:	XB-GENE-489141	Length:	343	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	70/219 - (31%)
Similarity:	113/219 - (51%)	Gaps:	27/219 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SNQTNSQDPQAVNSRIFVGNLNTFQCSKTDVERMFQIYGRLAGISMHKGYAFVQFTNPFDARNAC 71
            ||.||..||:::|||:|:|||||....|.|||.:|..||::.|.|:||||||||::|..:||.|.
Frog    64 SNVTNKTDPRSMNSRVFIGNLNTLVVKKADVEAIFSKYGKIVGCSVHKGYAFVQYSNERNARTAV 128

  Fly    72 HGEDGKTVLSQTLDVNMVAEPKAH--QIGRKRQNVSKTGNDWDY-------FYDSYCS------- 120
            .||||:.:..|.:|:|:.|||||:  :.|.||......|:.:|.       :||||.:
Frog   129 AGEDGRMIAGQVMDINLAAEPKANRSKTGVKRSAADMYGSSFDLEYDFQRDYYDSYSATRVPPPP 193

  Fly   121 --------SALLRGGGGAGGGGSNGVRAKKRKRLMTNGGGLAVAVQQQQQQHHHSAAAVAAAAAA 177
                    |...|..|.|...|.:|..:|..:|   .|...:..::....|......:.......
Frog   194 PIARAVVPSKRQRVSGNASRRGKSGFNSKSGQR---GGSSKSSRLKGDDLQAIKKELSQIKQRVD 255

  Fly   178 AVHQQQQQVQQQQQQQHHQQQQQQ 201
            ::.:..::::::|.:|..:..::|
Frog   256 SLLENLERIEREQSKQDIKLDEEQ 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42458	NP_996010.2	RRM	<11..>89	CDD:223796	40/77 (52%)
CG42458	NP_996010.2	RRM_hnRNPC_like	20..87	CDD:240787	35/66 (53%)
hnrnpc	XP_012815605.1	RRM_hnRNPC	76..146	CDD:241047	37/69 (54%)
hnrnpc	XP_012815605.1	APG6_N	<229..322	CDD:375248	4/51 (8%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I8954
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000671
OrthoInspector	1	1.000	-	-		otm48616
Panther	1	1.100	-	-	LDO	PTHR13968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8797
SonicParanoid	1	1.000	-	-		X853
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.040