Protein Alignment CG42458 and HNRNPC

DIOPT Version :9

• Sequence 1: NP_996010.2
• Gene: CG42458 / 2768945
• FlyBaseID: FBgn0259935
• Length: 711
• Species: Drosophila melanogaster
• Sequence 2: NP_001070910.1
• Gene: HNRNPC / 3183
• HGNCID: 5035
• Length: 306
• Species: Homo sapiens
• Alignment Length: 235
• Identity: 70/235 - (29%)
• Similarity: 110/235 - (46%)
• Gaps: 43/235 - (18%)

  Fly     7 SNQTNSQDPQAVNSRIFVGNLNTFQCSKTDVERMFQIYGRLAGISMHKGYAFVQFTNPFDARNAC 71
            ||.||..||:::|||:|:|||||....|:|||.:|..||::.|.|:|||:||||:.|..:||.|.
Human     3 SNVTNKTDPRSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIVGCSVHKGFAFVQYVNERNARAAV 67

  Fly    72 HGEDGKTVLSQTLDVNMVAEPKAH--QIGRKRQNVSKTGN-----------------DWDY---F 114
            .||||:.:..|.||:|:.||||.:  :.|.||......|:                 |:|:   :
Human    68 AGEDGRMIAGQVLDINLAAEPKVNRGKAGVKRSAAEMYGSVTEHPSPSPLLSSSFDLDYDFQRDY 132

  Fly   115 YDSYCS-----------------SALLRGGGGAGGGGSNGVRAKKRKRLMTNGGGL----AVAVQ 158
            ||...|                 |...|..|.....|.:|..:|..:|..:..|.|    ..|::
Human   133 YDRMYSYPARVPPPPPIARAVVPSKRQRVSGNTSRRGKSGFNSKSGQRGSSKSGKLKGDDLQAIK 197

  Fly   159 QQQQQHHHSAAAVAAAAAAAVHQQQQQVQQQQQQQHHQQQ 198
            ::..|......::.........:|.:|..:.:..:..::|
Human   198 KELTQIKQKVDSLLENLEKIEKEQSKQAVEMKNDKSEEEQ 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42458	NP_996010.2	RRM	<11..>89	CDD:223796	40/77 (52%)
		RRM_hnRNPC_like	20..87	CDD:240787	35/66 (53%)
HNRNPC	NP_001070910.1	RRM_hnRNPC	10..93	CDD:410015	43/82 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..190		9/50 (18%)
		Nuclear localization signal. /evidence=ECO:0000255	155..161		1/5 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	221..306		3/17 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	75	1.000	Domainoid score	I9051
eggNOG	1	0.900	-	-		E33208_3BCXK
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000671
OrthoInspector	1	1.000	-	-		otm41408
orthoMCL	1	0.900	-	-		OOG6_106780
Panther	1	1.100	-	-	LDO	PTHR13968
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8797
SonicParanoid	1	1.000	-	-		X853
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.840