DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-5 and rhbdl3

DIOPT Version :9

Sequence 1:	NP_995679.1	Gene:	rho-5 / 2768944	FlyBaseID:	FBgn0041723	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	XP_005166241.1	Gene:	rhbdl3 / 550128	ZFINID:	ZDB-GENE-050417-2	Length:	407	Species:	Danio rerio

Alignment Length:	184	Identity:	52/184 - (28%)
Similarity:	88/184 - (47%)	Gaps:	23/184 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly  1092 QLYRLLTSLCMHAGILHLAITLIFQHLFLADLERLIGTVRTAIVYIMSGFAGNLTSAILVPHRPE 1156
            |.:|.|:.:.|||||.||.:.:..|.|....||.:.|.:|..:||:....||:|..::.....|.
Zfish   213 QAWRFLSYIFMHAGIEHLGLNMAMQLLVGVPLEMVHGALRIGLVYVCGALAGSLAVSVTDMTAPV 277

  Fly  1157 VGPSASLSGVVASLIALLVWMHWKYLHKPHIALFKL-LLLCSVLVGIGTLPY------------Q 1208
            ||.|..:..:|::.:|.:| |:|..: |....||:: :.|..:.|..|...:            .
Zfish   278 VGSSGGVYALVSAHLANVV-MNWSGM-KCQFKLFRMAMALVCMSVEFGRAVWLRCYPPAFPPCPN 340

  Fly  1209 LNFLGLLAGVICGCLLTMSLVPFTTFSKYGRKKKINLIWTCVLFHVVVYTAMIV 1262
            .:|:..|.||..|  ||:.:|....:.:  |.::.:|.|  :.|.  |||..|:
Zfish   341 PSFVAHLGGVAVG--LTLGVVVLQNYEQ--RLQEQSLFW--IFFS--VYTLFIL 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-5	NP_995679.1	Rhomboid	1090..1225	CDD:279958	41/145 (28%)
rhbdl3	XP_005166241.1	EFh	35..95	CDD:238008
		EF-hand_7	35..94	CDD:290234
		Rhomboid	208..362	CDD:279958	44/152 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577611
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840