DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-5 and stet

DIOPT Version :9

Sequence 1:	NP_995679.1	Gene:	rho-5 / 2768944	FlyBaseID:	FBgn0041723	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_788450.1	Gene:	stet / 38169	FlyBaseID:	FBgn0020248	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	258	Identity:	67/258 - (25%)
Similarity:	98/258 - (37%)	Gaps:	73/258 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1080 GMFPFISVET------------------PD---QLYRLLTSLCMHAGILHLAITLIFQHLFLADL 1123
            |.|.:.||.|                  ||   :::|.|..:.:|||.|||...:..|.:|...|
  Fly   234 GFFVYHSVVTGEAAPRGPIPSDSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPL 298

  Fly  1124 ERLIGTVRTAIVYIMSGFAGNLTSAILVPHRPEVGPSASLSGVVASLIALLVWMHWKYLHKPHIA 1188
            |.:.|:.|.|.:|.....||:|.::|..|....||.|   .||.|.|.|.|..:...| |:....
  Fly   299 EMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGAS---GGVYALLAAHLANVLLNY-HQMRYG 359

  Fly  1189 LFKLL-LLCSVLVGIGTLPY--------------------------QLNFLGLLAGVICGCLLTM 1226
            :.||| :|..|....|...|                          .::::..|||.|.|  ||:
  Fly   360 VIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAG--LTI 422

  Fly  1227 SLVPFTTFSKYGRKKKINLIWTCVLFHVVVYTAMIVTFYIHPSEFHSISFVDMFSNSNGYDNF 1289
            .|:...:|.   :|....|:|...|   ..|.|::|             |...|:..||:..|
  Fly   423 GLLVLKSFE---QKLHEQLLWWIAL---GTYLALVV-------------FAIAFNIMNGFAMF 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-5	NP_995679.1	Rhomboid	1090..1225	CDD:279958	46/164 (28%)
stet	NP_788450.1	EFh	<75..115	CDD:298682
		EF-hand_7	91..156	CDD:290234
		Rhomboid	262..428	CDD:279958	49/171 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444954
Domainoid	1	1.000	84	1.000	Domainoid score	I2842
eggNOG	1	0.900	-	-		E1_COG0705
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3549
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.740