DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rho-5 and rom-2

DIOPT Version :9

Sequence 1:	NP_995679.1	Gene:	rho-5 / 2768944	FlyBaseID:	FBgn0041723	Length:	1429	Species:	Drosophila melanogaster
Sequence 2:	NP_001366679.1	Gene:	rom-2 / 183564	WormBaseID:	WBGene00004401	Length:	348	Species:	Caenorhabditis elegans

Alignment Length:	200	Identity:	47/200 - (23%)
Similarity:	78/200 - (39%)	Gaps:	38/200 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly  1092 QLYRLLTSLCMHAGILHLAITLIFQHLFLADLERLIGTVRTAIVYIMSGFAGNLTSAILVPHRPE 1156
            :|:||.|...::.||.|:...::.|......|| |:...|..|:|.|....|::.|..|.|....
Worm   168 ELWRLFTYCLINVGIFHIIFNILIQLAIGVPLE-LVHRWRIYILYFMGVLFGSILSLALDPTVFL 231

  Fly  1157 VGPSASLSGVVASLIALLVWMHWKYLHKPHIALFKLLLLCSVLVGIGTLPY-------------- 1207
            .|.:|....::||.|..:. .::|.:......|       .:|:....|.|
Worm   232 CGGAAGSFSLIASHITTIA-TNFKEMENATCRL-------PILIVFAALDYVLAVYQRFFAPRID 288

  Fly  1208 QLNFLGLLAGVICGCLLTMSLVPFTTFSKYGRKKKINLIWTCVLFHVVV-----YTAMIVTFYIH 1267
            :::..|.|.|::.|.|.|..|.         |..|.:..:| |.|.|.:     :.|:.:|....
Worm   289 KVSMYGHLGGLVAGILFTFILF---------RGSKPSRFYT-VSFWVSLVLSGFFIAICITLIAA 343

  Fly  1268 PSEFH 1272
            ||..|
Worm   344 PSMLH 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rho-5	NP_995679.1	Rhomboid	1090..1225	CDD:279958	34/146 (23%)
rom-2	NP_001366679.1	EF-hand_7	21..82	CDD:404394
rom-2	NP_001366679.1	Rhomboid	165..311	CDD:396315	36/160 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0705
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810