Protein Alignment CG33296 and Slc6a2

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_112633.2
• Gene: Slc6a2 / 83511
• RGDID: 621822
• Length: 617
• Species: Rattus norvegicus
• Alignment Length: 562
• Identity: 136/562 - (24%)
• Similarity: 248/562 - (44%)
• Gaps: 54/562 - (9%)

  Fly    20 RGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQFS 83
            |..|.|..|:|.:..|.|:.| :::...|..:.|.|...::||.|:::|..:|:..:...:|||:
  Rat    56 RETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFN 120

  Fly    84 SSGFIAAFRLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSWH--N 146
            ..|....:::.|.|||:||..|.:......||::.:|..|.:|..||...|||:..| .:|:  |
  Rat   121 REGAATVWKICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCG-HAWNSPN 184

  Fly   147 RTDEYPTLCHPTIYKQHENYTLGVEAPSRLYFDYIRQDYFNTDKRFDISRPLIGLFTLSWALIAI 211
            .||  |.|.:.::...|..|:.....|:..:::........:....||..|...|......:|.:
  Rat   185 CTD--PKLLNASVLGDHTKYSKYKFTPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVV 247

  Fly   212 IFYHFSEPAK-FGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYITPNTKDFSEGIYSTFI- 274
            :::...:..| .||.:.........::.|..|..:.|||:...:..|:..:.....|.  :.:|
  Rat   248 LYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEA--TVWID 310

  Fly   275 MALQAF---GAGWGSVIALSSFNGFKTD-------IMSYSWIISFGQIFIYIMFGLVSFMLEQYY 329
            .|.|.|   |||:|.:||.:|:|.|..:       ..:.:.:.||  |..:.:|.::.:|..::.
  Rat   311 AATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSF--ISGFAIFSILGYMAHEHK 373

  Fly   330 KDISDTIVFHRIMNFWVLFLSSASALNTLGWPNLWTFIYYSMLLLASLTVIATQLFTVLQSLFDE 394
            ..|.|...    ....::|:....|::||.....|..:::.|||...|......:..|:..|.|:
  Rat   374 VKIEDVAT----EGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADD 434

  Fly   395 FEKLKERKQEVTFGIICGLAICSFFFCTEHGSFYFAILGIDVILA-HSLLHLLLL--LVVLWIYG 456
            |:.||..::..|..:..|..:.:.|..|:.|.:...:|  |...| .|:|..:|:  :.|.|.||
  Rat   435 FQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLL--DTFAAGTSILFAVLMEAIGVSWFYG 497

  Fly   457 QKRFQRDIEFMLG-QPFASWKVFILRYTAPIVFLICMILGIIECIRVHFFFKEV----------- 509
            ..||..||:.|:| :|...|:: ..::.:|...|..:::.||.       ||.:
  Rat   498 VDRFSNDIQQMMGFKPGLYWRL-CWKFVSPAFLLFVVVVSIIN-------FKPLTYDDYVYPPWA 554

  Fly   510 -FLVLGIILVVLPFLAIPGYGFYYLRQSPGTFLERLKRSCRP 550
             ::..||.|..:  :.:|.|..|......|:..||:.....|
  Rat   555 NWVGWGIALSSM--ILVPAYVIYKFFSIRGSLWERVAYGITP 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	119/487 (24%)
Slc6a2	NP_112633.2	SLC5-6-like_sbd	56..615	CDD:444915	136/562 (24%)