Protein Alignment CG33296 and SLC6A12

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_003035.3
• Gene: SLC6A12 / 6539
• HGNCID: 11045
• Length: 614
• Species: Homo sapiens
• Alignment Length: 603
• Identity: 129/603 - (21%)
• Similarity: 255/603 - (42%)
• Gaps: 115/603 - (19%)

  Fly    20 RGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQFS 83
            ||:|....:::.:..|..:.| :::...|..:.|.|....:|||::..:..:|:..:...:||::
Human    36 RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYT 100

  Fly    84 SSGFIAAFR-LAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPW-SCEGLKSWHN 146
            |.|.:.|:| :.|||:|:|..|:.:.....:||.:.:|..|.:|.:||...||| :|...  |:.
Human   101 SQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNF--WNT 163

  Fly   147 RTDEYPTLCHPTIYKQH---------ENYTLGVEAPSRLYFDYIRQDYFNTDKRFDISRPLIGLF 202
            .        |.|.:..|         ||:|    :|...:::         .:...|:..:..|.
Human   164 E--------HCTDFLNHSGAGTVTPFENFT----SPVMEFWE---------RRVLGITSGIHDLG 207

  Fly   203 TLSW-----ALIAIIFYHF---SEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYIT 259
            :|.|     .|:|.:..:|   ......||.:.:......:::|:..:|.:.|||:::.:..|:.
Human   208 SLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLK 272

  Fly   260 PNT---------KDFSEGIYSTFIMALQAFGAGWGSVIALSSFNGFKT----DIMSYSWIISFGQ 311
            |:.         .|....|:.:|.:.       .|.:.||.|:|.:..    |.::..::.| ..
Human   273 PDLFRLKDPQVWMDAGTQIFFSFAIC-------QGCLTALGSYNKYHNNCYKDCIALCFLNS-AT 329

  Fly   312 IFI--YIMFGLVSFMLEQYYKDISDTIVFHRIMNFWVLFLSSASALNTLGWPNLWTFIYYSMLL- 373
            .|:  :::|.::.||.::....||:...    ....:.|::...|:..:....||:.:::.||:
Human   330 SFVAGFVVFSILGFMSQEQGVPISEVAE----SGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIF 390

  Fly   374 --LASLTVIATQLFTVLQSLFDEFEKLKERKQE---VTFGIICGLAICSFFFCTEHGSF------ 427
              |.|..|....|.|....:|.. :..|..::|   :|..::|.|  ...|..||.|.:
Human   391 LGLDSQFVCVECLVTASIDMFPR-QLRKSGRRELLILTIAVMCYL--IGLFLVTEGGMYIFQLFD 452

  Fly   428 YFAILGIDVILAHSLLHLLLLLVVLWIYGQKRFQRDIEFMLGQPFASWKVFILRYTAPIVFLICM 492
            |:|..||.::    .|.|..::.:.|:||..||..:||.|:|  :..|         |:|.:..:
Human   453 YYASSGICLL----FLSLFEVVCISWVYGADRFYDNIEDMIG--YRPW---------PLVKISWL 502

  Fly   493 ILGIIECIRVHFF---------FKEVFLV------LGIILVVLPFLAIPGYGFYYLRQSPGTFLE 542
            .|....|:....|         :..|::.      :|..|.:...:.:|.:....|.::.|.|.:
Human   503 FLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRK 567

  Fly   543 RLKRSCRPTDWYPVEMKH 560
            ||::...|....|...:|
Human   568 RLRQLITPDSSLPQPKQH 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	112/515 (22%)
SLC6A12	NP_003035.3	SLC6sbd_BGT1	35..575	CDD:212080	126/591 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	576..614		2/10 (20%)