Protein Alignment CG33296 and SLC6A11

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_055044.1
• Gene: SLC6A11 / 6538
• HGNCID: 11044
• Length: 632
• Species: Homo sapiens
• Alignment Length: 611
• Identity: 121/611 - (19%)
• Similarity: 257/611 - (42%)
• Gaps: 122/611 - (19%)

  Fly    19 KRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQF 82
            :||.|....:::.:..|..:.| :::...|..:.|.|...::||.::.:...:|:..:.:.:|||
Human    49 ERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCGIPVFFLETALGQF 113

  Fly    83 SSSGFIAAFR-LAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSWHN 146
            :|.|.|..:| :.|||:|:||.:..:.....:||.:.:|..:.:|.|.|...|||:..| ..|:.
Human   114 TSEGGITCWRKVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTELPWATCG-HEWNT 177

  Fly   147 RT-DEYPTL-----CHPTI---------YKQHENYTL--GVEAPSRLYFDYIRQDYFNTDKRFDI 194
            .. .|:..|     .|.::         :.:|....:  |:|....|              |:::
Human   178 ENCVEFQKLNVSNYSHVSLQNATSPVMEFWEHRVLAISDGIEHIGNL--------------RWEL 228

  Fly   195 SRPLIGLFTLSWALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYIT 259
            :..|:..:|:.:      |..:......||.:........:::::..:|.:.|||:.:.:..|:.
Human   229 ALCLLAAWTICY------FCIWKGTKSTGKVVYVTATFPYIMLLILLIRGVTLPGASEGIKFYLY 287

  Fly   260 PNTKDFSE---------GIYSTFIMALQAFGAGWGSVIALSSFNGFKTD-----IMSYSWIISFG 310
            |:....|:         .|:.::.:.|       |.:.||.|:|.:..:     ||  ...::.|
Human   288 PDLSRLSDPQVWVDAGTQIFFSYAICL-------GCLTALGSYNNYNNNCYRDCIM--LCCLNSG 343

  Fly   311 QIFI--YIMFGLVSFMLEQYYKDISDTIVFHRIMNFWVLFLSSASALNTLGWPNLWTFIYYSMLL 373
            ..|:  :.:|.::.||..:....|::...    ....:.|::...|:..:....||..:::.||:
Human   344 TSFVAGFAIFSVLGFMAYEQGVPIAEVAE----SGPGLAFIAYPKAVTMMPLSPLWATLFFMMLI 404

  Fly   374 LASLTVIATQLFTVLQSLFDEFEKLKER--KQEVTFGIICGLAICSFF----FCTEHGSFYFAIL 432
            ...|......:.:::.::.|.:.|:..|  ::|:   :|..|::.|:|    ..||.|.:.|.:.
Human   405 FLGLDSQFVCVESLVTAVVDMYPKVFRRGYRREL---LILALSVISYFLGLVMLTEGGMYIFQLF 466

  Fly   433 GIDVILAHSLLHLLLLLVVL-------WIYGQKRFQRDIEFMLGQPFASWKVFILRYTAPIVFLI 490
            .     :::...:.||.|.:       |:||..||..:||.|:|            |..|.:...
Human   467 D-----SYAASGMCLLFVAIFECICIGWVYGSNRFYDNIEDMIG------------YRPPSLIKW 514

  Fly   491 CMIL---GIIECIRVHFFFK-------EVFLV------LGIILVVLPFLAIPGYGFYYLRQSPGT 539
            |.::   ||...|.:.|..|       .::..      :|.::.:...|.||.:....:.::.||
Human   515 CWMIMTPGICAGIFIFFLIKYKPLKYNNIYTYPAWGYGIGWLMALSSMLCIPLWICITVWKTEGT 579

  Fly   540 FLERLKRSCRPTDWYPVEMKHRQHYG 565
            ..|:|::...|:    .::|.|...|
Human   580 LPEKLQKLTTPS----TDLKMRGKLG 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	101/519 (19%)
SLC6A11	NP_055044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41
		SLC6sbd_GAT3	49..590	CDD:212077	117/594 (20%)