Protein Alignment CG33296 and SLC6A8

DIOPT Version :9

• Sequence 1: NP_001285711.1
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_005620.1
• Gene: SLC6A8 / 6535
• HGNCID: 11055
• Length: 635
• Species: Homo sapiens
• Alignment Length: 628
• Identity: 151/628 - (24%)
• Similarity: 250/628 - (39%)
• Gaps: 128/628 - (20%)

  Fly    18 PKRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQ 81
            |.|..|.:..|::.:|.|.|:.| :::...|..:.|.|.|.::||.|..::..:||..:...:||
Human    50 PPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQ 114

  Fly    82 FSSSGFIAAFRLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSWH- 145
            |..:|.|..:.:.|||||:||.|:.:.|....||.|.:|....:|:.||..||||:..| .:|:
Human   115 FMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCG-HTWNT 178

  Fly   146 ------------------NRT-DEYPTLCHPTIYKQHENYTL----GVEAPSRLYFDYIRQDYFN 187
                              |.| |:......|.| :..||..|    |:|.|..|
Human   179 PDCVEIFRHEDCANASLANLTCDQLADRRSPVI-EFWENKVLRLSGGLEVPGAL----------- 231

  Fly   188 TDKRFDISRPLIGLFTLSWALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHK 252
               .::::..|:.    .|.|  :.|..:......||.:.:......|::||..||.:.|||:..
Human   232 ---NWEVTLCLLA----CWVL--VYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALD 287

  Fly   253 LLWMYITPNTKDFSE-GIYSTFIMA----LQAFGAGWGSVIALSSFNGFKTDIMSYSWI---ISF 309
            .:..|:.|   |:|: |....:|.|    ..::..|.|::.||.|:|.|..:....:.|   |:.
Human   288 GIIYYLKP---DWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINS 349

  Fly   310 GQIFI--YIMFGLVSFMLEQYYKDISDTIVFHRIMNFWVLFLSSASALNTLGWPN---------L 363
            |..|.  :::|.::.||..:....||..             ..|...|..:.:|.         |
Human   350 GTSFFAGFVVFSILGFMAAEQGVHISKV-------------AESGPGLAFIAYPRAVTLMPVAPL 401

  Fly   364 WTFIYYSMLLLASLTV-------IATQLFTVL-QSLFDEFEKLKERKQEVTFGIICGLA-ICSFF 419
            |..:::.||||..|..       ..|.|..:| .|.:..|::      |::..:.|.|. :....
Human   402 WAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQR------EISVALCCALCFVIDLS 460

  Fly   420 FCTEHGSFYFAILGIDVILAHSLLHLLL--LLVVLWIYGQKRFQRDIEFMLGQPFASWKVFILRY 482
            ..|:.|.:.|.:.........:||....  .:||.|:||..||..||..|:|.....|..:...:
Human   461 MVTDGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMKWCWSF 525

  Fly   483 TAPIVFLICMILGIIECIRVHFFFKEVFL----------------VLGIILVVLPFLAIPGYGFY 531
            ..|   |:||  ||       |.|..|:.                .:|....:...|.:|.:...
Human   526 FTP---LVCM--GI-------FIFNVVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVPLHLLG 578

  Fly   532 YLRQSPGTFLERLKRSCRPTDWYPVEMKHRQHYGDRVGNIEMT 574
            .|.::.||..||.:...:|. |....:::|....|..|...:|
Human   579 CLLRAKGTMAERWQHLTQPI-WGLHHLEYRAQDADVRGLTTLT 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	129/523 (25%)
SLC6A8	NP_005620.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..28
		SLC6sbd_CT1	52..621	CDD:271397	150/626 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910