DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33296 and si:ch211-132b12.6

DIOPT Version :9

Sequence 1:	NP_001285711.1	Gene:	CG33296 / 2768941	FlyBaseID:	FBgn0053296	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001038523.1	Gene:	si:ch211-132b12.6 / 564583	ZFINID:	ZDB-GENE-050420-179	Length:	577	Species:	Danio rerio

Alignment Length:	592	Identity:	131/592 - (22%)
Similarity:	254/592 - (42%)	Gaps:	70/592 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 KRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQF 82
            :||.|.|..::|.|..|..:.| :::...|..:.|.|.|.::||.:::|...:|:.::.:.||||
Zfish    10 ERGFWGKKAEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGLPLFLLETAMGQF 74

  Fly    83 SSSGFIAAF-RLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPW-SCEGLKSWH 145
            :..|.|..: ||.||.:|:||........:.:||::.:|..|.:|::||...||| ||..:  |:
Zfish    75 THEGGITCWHRLCPLAQGVGYAGQLTVLYSCMYYTIILAWALFYLVSSFSSQLPWVSCNNI--WN 137

  Fly   146 NRTDEYPTLCHPTIYKQHENYTLGVEAPSRLYFDYIRQDYFNTDKR-FDISRPLIGLFTLSW--- 206
              ||....|....:............|.:..:           ::| ..:|..:..:..::|
Zfish   138 --TDNCVNLAAGNLTFNRTTLANSTSAATEFW-----------ERRVLSLSGGIEDIGKINWEIL 189

  Fly   207 -ALIA--IIFYH--FSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYITPNTKDFS 266
             .|||  ||.|.  :......||.:.:......|:::|..:|.|.|||:.:.:..|:.|.....:
Zfish   190 LCLIAMWIICYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLYPEPARLA 254

  Fly   267 E-------GIYSTFIMALQAFGAGWGSVIALSSFNGFKTDIMSYS-W--IISFGQIFI--YIMFG 319
            :       |....|     ::....|.:|:|.|:|.:..:....| |  :::.|..|:  :.:|.
Zfish   255 DPQVWMEAGTQVFF-----SYSVCSGILISLGSYNQYSNNCYRDSFWLCLLNSGTSFVAGFAVFS 314

  Fly   320 LVSFMLEQY---YKDISDTIVFHRIMNFWVLFLSSASALNTLGWPNLWTFIYYSMLLLASLTVIA 381
            ::.||....   .::::::       ...:.|::...|:..:.:|.||...::.|::|..|....
Zfish   315 VLGFMAHVQGVPVEEVAES-------GPGLAFIAYPQAMAMMPFPQLWAVCFFIMIILLGLDSQF 372

  Fly   382 TQLFTVLQSLFDEFEKLKER--KQEVTFGIICGLAICSF---FFCTEHGSFYFAILGIDVILAHS 441
            ..:..|:.|:.|.|.::..|  ::|:...::|  ..|.|   ...||.|.:.|.:..........
Zfish   373 VGIECVITSVMDLFPEVLRRAGRRELFVLLLC--LTCFFGQLIMVTEGGMYVFQLFDNYACNGAC 435

  Fly   442 LLHLLLL--LVVLWIYGQKRFQRDIEFMLGQPFASWKVFILRYTAPIVFLICMILGIIECIRVHF 504
            ||.|.:.  |.:.|::|.::....||.|.......|.:...:|..|:|.|:..:..::....:.|
Zfish   436 LLFLSVFESLAIGWLFGAEKMFDIIEDMTESRPNYWFMLCWKYLTPLVSLMSFVYSMVRYTPLTF 500

  Fly   505 ----FFKEVFLVLGIILVVLPFLAIPGYGFYYLRQSPGTFLERLKRSCRPTDWYPVEMKHRQHYG 565
                .:.:....||.:|.:...|.:||:....:....||..:|....|.|.....:..|..|
Zfish   501 NRWYVYPDWAYALGWLLALSSILLVPGWALGQMWAGKGTLKQRWGHLCSPETKLMLSFKQIQ--- 562

  Fly   566 DRVGNIE 572
            |:...:|
Zfish   563 DQFAEME 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	111/502 (22%)
si:ch211-132b12.6	NP_001038523.1	SLC6sbd-TauT-like	11..550	CDD:271387	126/567 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010