Protein Alignment CG33296 and SLC6A15

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_877499.1
• Gene: SLC6A15 / 55117
• HGNCID: 13621
• Length: 730
• Species: Homo sapiens
• Alignment Length: 608
• Identity: 122/608 - (20%)
• Similarity: 231/608 - (37%)
• Gaps: 129/608 - (21%)

  Fly    17 DPKRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMG 80
            :.:|..|.....|:.|..|.::.| :::...|....|.|...:|||.:.:::..:|:..:...:|
Human    58 EDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLLPYLILLMVIGIPLFFLELSVG 122

  Fly    81 QFSSSGFIAAFR-LAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSW 144
            |....|.|..:. ::|...|:|:.|..:.:...:||::.:...|.:...||:..|||
Human   123 QRIRRGSIGVWNYISPKLGGIGFASCVVCYFVALYYNVIIGWSLFYFSQSFQQPLPW-------- 179

  Fly   145 HNRTDEYPTL---CHPTIYKQHENYTLGVEAPSRLYFDYIRQDYFNTDKRFDISRPLIGLFTL-- 204
                |:.|.:   .|..:..:.|      ::.:..|:.|  ::..|.......|..|....|:
Human   180 ----DQCPLVKNASHTFVEPECE------QSSATTYYWY--REALNISSSISESGGLNWKMTICL 232

  Fly   205 --SWALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCF-VRFLFLPGSHKLLWMYITP------ 260
              :|.::.:......:.:  ||.|.:..:...| |::|| :|...|.||...:....||
Human   233 LAAWVMVCLAMIKGIQSS--GKIIYFSSLFPYV-VLICFLIRAFLLNGSIDGIRHMFTPKLEIML 294

  Fly   261 NTKDFSEGIYSTFIMALQAFGAGWGSVIALSSFNGFKTDIMSYSWIISFGQIFIYIMFGLVSF-- 323
            ..|.:.|.....|.    |.|.|:|.|||.||:|....:....:.::||...|..::..||.|
Human   295 EPKVWREAATQVFF----ALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAV 355

  Fly   324 ------------------MLEQYYK--DISDTIVFHRI--------------------------- 341
                              .:.::.|  :||..|:.|.|
Human   356 LGFKANVINEKCITQNSETIMKFLKMGNISQDIIPHHINLSTVTAEDYHLVYDIIQKVKEEEFPA 420

  Fly   342 ----------------MNFWVLFLSSASALNTLGWPNLWTFIYYSMLLLASLTVIATQLFTVLQS 390
                            ....:.|::...|:........|:.:::.||:...|..:...:..::..
Human   421 LHLNSCKIEEELNKAVQGTGLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIVTP 485

  Fly   391 LFDEFEKLKERKQEVTFGIICGLAICSFFFCTEHGSFYFAILGIDVILAHSLLHLLLL--LVVLW 453
            :.|.|   |.||:.:|. |.|.||.|......:....||..:..|......||.:::|  :.|.:
Human   486 IVDTF---KVRKEILTV-ICCLLAFCIGLIFVQRSGNYFVTMFDDYSATLPLLIVVILENIAVCF 546

  Fly   454 IYGQKRFQRDIEFMLGQPFASWKVFILRYTAPIVFLICMILGIIEC--------IRVHFFFKEVF 510
            :||..:|..|::.|||...:.:..::.:|.:|::.|..:|..::..        ..:.....|.|
Human   547 VYGIDKFMEDLKDMLGFAPSRYYYYMWKYISPLMLLSLLIASVVNMGLSPPGYNAWIEDKASEEF 611

  Fly   511 -------LVLGIILVVLPFLAIP 526
                   ||:.:.|||...|.:|
Human   612 LSYPTWGLVVCVSLVVFAILPVP 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	111/551 (20%)
SLC6A15	NP_877499.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	41..60		0/1 (0%)
		SLC6sbd_SBAT1	61..640	CDD:212091	122/605 (20%)