Protein Alignment CG33296 and SLC6A20

DIOPT Version :9

• Sequence 1: NP_001285711.1
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001372612.1
• Gene: SLC6A20 / 54716
• HGNCID: 30927
• Length: 603
• Species: Homo sapiens
• Alignment Length: 652
• Identity: 136/652 - (20%)
• Similarity: 250/652 - (38%)
• Gaps: 185/652 - (28%)

  Fly    20 RGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQFS 83
            |..|.....::|||...|:.| :::...|......|...::||.:.:::..:|:|.:...:||..
Human     5 RPLWANSLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYIIMLIVEGMPLLYLELAVGQRM 69

  Fly    84 SSGFIAAFR-LAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSWHNR 147
            ..|.|.|:| ::|...|:|..|:.::|...:||::..|....:|.:||:..||||...|...|..
Human    70 RQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWAFWYLFHSFQDPLPWSVCPLNGNHTG 134

  Fly   148 TDEYPTLCHPTIYKQHENYTLGVEAPSRLYFDYIRQDYFNTDKRFDIS-----------RPLIGL 201
            .||.   |.              :|.|..||.|        .|..:||           .|.:.|
Human   135 YDEE---CE--------------KASSTQYFWY--------RKTLNISPSLQENGGVQWEPALCL 174

  Fly   202 FTLSWALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYITPNTKDFS 266
            . |:|.::.:.....:|..  ||.:.:.......::::..:|.|.|.|:...|....||
Human   175 L-LAWLVVYLCILRGTEST--GKVVYFTASLPYCVLIIYLIRGLTLHGATNGLMYMFTP------ 230

  Fly   267 EGIYSTFIMALQ-------------------AFGAGWGSVIALSSFNGFKTDIMSYSWIIS---- 308
            :|..:..::|.|                   :.|.|:||:||.:|:|....:...::.|:|
Human   231 KGSSALSLLAFQIEQLANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNNCQKHAIIVSLINS 295

  Fly   309 ----FGQIFIYIMFGL------------VSFMLEQYYKDISD----------------------- 334
                |..|..:.::|.            ||.:|...: |:.|
Human   296 FTSIFASIVTFSIYGFKATFNYENCLKKVSLLLTNTF-DLEDGFLTASNLEQVKGYLASAYPSKY 359

  Fly   335 TIVFHRIMN-------------FWVLFLSSASALNTLGWPNLWTFIYYSMLLLASLTVIATQLFT 386
            :.:|.:|.|             ..:.|:....|:..:....||:.:|:.|||:..:..:......
Human   360 SEMFPQIKNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGIGSMLGNTAA 424

  Fly   387 VLQSLFDEFEKLKERKQEVTFGIICGLAICS--FFFCTEHGSFYFAILGIDVILAHSLLHLLLL- 448
            :|..|.|.........:|...|::| |..|:  ..|..|.|:::|.|.. |.....|||.::|:
Human   425 ILTPLTDSKIISSHLPKEAISGLVC-LVNCAIGMVFTMEAGNYWFDIFN-DYAATLSLLLIVLVE 487

  Fly   449 -LVVLWIYGQKRFQRDIEFMLGQPFA-SWKVFILRYTAPIVFLICMILGIIECIRVHFFFKEVFL 511
             :.|.::||.:||:.|::.|.|:..: .||| :....:|::.:...:          |:..:..|
Human   488 TIAVCYVYGLRRFESDLKAMTGRAVSWYWKV-MWAGVSPLLIVSLFV----------FYLSDYIL 541

  Fly   512 ---------------------------VLGIIL----VVLPFLAIPGYGFYYLRQSPGTFLE-RL 544
                                       |:|:::    :.:|..|:            |||:: ||
Human   542 TGTLKYQAWDASQGQLVTKDYPAYALAVIGLLVASSTMCIPLAAL------------GTFVQRRL 594

  Fly   545 KR 546
            ||
Human   595 KR 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	121/561 (22%)
SLC6A20	NP_001372612.1	SLC6sbd_SIT1	2..588	CDD:271401	129/642 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810