DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33296 and List

DIOPT Version :9

Sequence 1:	NP_001285711.1	Gene:	CG33296 / 2768941	FlyBaseID:	FBgn0053296	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_611364.2	Gene:	List / 37157	FlyBaseID:	FBgn0034381	Length:	564	Species:	Drosophila melanogaster

Alignment Length:	564	Identity:	130/564 - (23%)
Similarity:	255/564 - (45%)	Gaps:	50/564 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 KWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQFSSS 85
            :|....::||:|..|::.| :|:...|..|.|.|...::||.:.:::...|:..:...:|||:..
  Fly    20 QWGNGLEFLFSCISLSVGLGNIWRFPYIAFQNGGGTFVIPYLIALLVIGRPVYYLEISLGQFTGR 84

  Fly    86 GFIAAFRLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSWHNRTDE 150
            |.:.||.:|||.||:....:..|..::.|||..:|:.|.|.:.||...||||    :.|    :.
  Fly    85 GVVKAFDMAPLLKGVALGQVLATAASITYYSSIMALTLRFWLASFGSELPWS----RCW----ES 141

  Fly   151 YPTLCHPTIYKQHENYTLGVEAPSRLYFD-YIRQDYFNTDKRFDISRP---LIGLFTLSWALIAI 211
            :.|.||    ..:...:.|..:|::|||: .|..:..|.|.  .:|.|   |:....::|.:|..
  Fly   142 WGTDCH----DGNAQNSSGKMSPAQLYFEREILHEVPNIDN--GLSLPNWQLVACLAIAWLVIGG 200

  Fly   212 IFYHFSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYITPNTKDFSEGI--YSTFI 274
            :.....:.:  ||...::.:...|::::..:|.:.|||:...:..:..|..::....:  |:...
  Fly   201 VLIRGIKSS--GKAAYFLGVFPYVVLLILLLRAVTLPGAIDGIIYFFKPQWRELLNPLVWYAAVT 263

  Fly   275 MALQAFGAGWGSVIALSSFNGFKTDIMSYSWIISFGQIFIYIMFGLVSFML------EQYYKDIS 333
            ....:....:|::|..:|:|.|..::.:...||:.......|:.|.::|.:      |....||.
  Fly   264 QVFFSLAICFGTLITYASYNNFNRNVYNDIVIITTMDSCSSIIAGCITFGILGNLARETGNPDIG 328

  Fly   334 DTIVFHRIMNFWVLFLSSASALNTLGW-PNLWTFIYYSMLLLASLTVIATQLFTVLQSLFDEFEK 397
            ..:.    ....:.|:|...|:....: |.::..:::.||.:..:.........:|:.:.|:|..
  Fly   329 SVVK----GGAGLAFISYPEAIAKFEYVPQMFAVLFFLMLFVLGIGSTVGMGSCILRVIRDQFGL 389

  Fly   398 LKERKQEVTFGI-ICGLAICSFFFCTEHGSFYFAILGIDVILAHSLLHLLL----LLVVLWIYGQ 457
            ......::..|: :.|.:: |..:.|..|.|   ||.:......|...|:|    |:.|.||||.
  Fly   390 RSPPIWKLASGLTVLGFSV-SIVYMTPGGQF---ILNLVDFYGVSFTALILAIGELVAVAWIYGV 450

  Fly   458 KRFQRDIEFMLGQPFASWKVFILRYTAPIVFLICMILGIIECIRVHF---FFKEVFLVLGIILVV 519
            .||..||:||:|.....:.....|:..|.:....:|..:::...:.:   .:..:..|.|..|..
  Fly   451 NRFCEDIKFMMGIETGWYWRLCWRFITPGLMTAVLIYMLLDMSALEYKGVGYPTLAHVFGCFLAT 515

  Fly   520 LPFLAIPG---YGFYYLRQSPGTFLERLKRSCRPTD-WYPVEMK 559
            |..:.:||   |..|..|...|:|.:|::.:|:|:| |.|..::
  Fly   516 LGLIQLPGWAIYAIYKKRGHNGSFWQRIRAACKPSDTWGPANVQ 559

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	112/487 (23%)
List	NP_611364.2	SLC6sbd	19..489	CDD:271359	113/492 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440797
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840