Protein Alignment CG33296 and SLC6A18

DIOPT Version :9

• Sequence 1: NP_001285711.1
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_872438.2
• Gene: SLC6A18 / 348932
• HGNCID: 26441
• Length: 628
• Species: Homo sapiens
• Alignment Length: 662
• Identity: 145/662 - (21%)
• Similarity: 249/662 - (37%)
• Gaps: 185/662 - (27%)

  Fly    16 PDP-------KRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPI 72
            |||       :|.||:....||.:|.|.|:.| :|:...|......|...::||.:.:|...:||
Human     7 PDPAACDLGDERPKWDNKAQYLLSCTGFAVGLGNIWRFPYLCQTYGGGAFLIPYVIALVFEGIPI 71

  Fly    73 LVVHSFMGQFSSSGFIAAF-RLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPW 136
            ..|...:||....|.:..: .::|...|:|...:.|:|...:||:..||..|.:|:|||:..|||
Human    72 FHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVAWVLWYLLNSFQHPLPW 136

  Fly   137 S--------------CEGLKS----WHNRTDEYPTLCHPTIYKQHENYTLGVEAPSRLYFDYIRQ 183
            |              |:|..:    |               |:|..|.|..:....
Human   137 SSCPPDLNRTGFVEECQGSSAVSYFW---------------YRQTLNITADINDSG--------- 177

  Fly   184 DYFNTDKRFDISRPLIGLFTLSWALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLP 248
                     .|...|:.....|||::.:......|..  ||.|.:..:...:::.:..:|.|.||
Human   178 ---------SIQWWLLICLAASWAVVYMCVIRGIETT--GKVIYFTALFPYLVLTIFLIRGLTLP 231

  Fly   249 GSHKLLWMYITPNTK---------DFSEGIYSTFIMALQAFGAGWGSVIALSSFNGFKTDIMSYS 304
            |:.|.|....|||..         |.:..|:.:..:|       :|..||.:|:|..:.|....:
Human   232 GATKGLIYLFTPNMHILQNPRVWLDAATQIFFSLSLA-------FGGHIAFASYNSPRNDCQKDA 289

  Fly   305 WIIS----FGQIFIYI-MFGLVSFMLEQYYKDISDTIVFHRIMNF-------------------- 344
            .:|:    ...::..| :|.::.|.....|:...|..:...|.:|
Human   290 VVIALVNRMTSLYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLN 354

  Fly   345 --WVL--------------FLSSASA-------------LNTLGWPNLWTFIYYSMLLLASLTVI 380
              |..              ||..:::             |:..|.| :|..:::.||....|:.:
Human   355 ATWPKRVAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAP-VWAMLFFGMLFTLGLSTM 418

  Fly   381 ATQLFTVLQSLFDEFEKLKERKQEVTFGIICGLAIC---SFFFCTEHGSFYFAILGIDVILAHSL 442
            ...:..|:..|.|.....:...:|...|::|  .:|   :..|..:.|:::..|.. :...:.:|
Human   419 FGTVEAVITPLLDVGVLPRWVPKEALTGLVC--LVCFLSATCFTLQSGNYWLEIFD-NFAASPNL 480

  Fly   443 LHLLLLLV--VLWIYGQKRFQRDIEFMLG-QPFASWKVFILRYTAPI---VFLICMILGIIECIR 501
            |.|..|.|  |:::||.|||..||.:|.| :|...|:: ..|..:|:   :|:..:||
Human   481 LMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRL-TWRVVSPLLLTIFVAYIIL------- 537

  Fly   502 VHFFFK-----------EVF------LVLG------IILVVLPFLAIPGYGFYYLRQSPGTFLER 543
              .|:|           |:|      |..|      ::|.:||.|.:|......|       |.|
Human   538 --LFWKPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAALAQL-------LTR 593

  Fly   544 LKRSCRPTDWYP 555
            .:|:.|..|..|
Human   594 RRRTWRDRDARP 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	121/560 (22%)
SLC6A18	NP_872438.2	SLC6sbd_B0AT3	17..591	CDD:212086	136/636 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	602..628		2/4 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810