Protein Alignment CG33296 and SLC6A19

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_001003841.1
• Gene: SLC6A19 / 340024
• HGNCID: 27960
• Length: 634
• Species: Homo sapiens
• Alignment Length: 630
• Identity: 140/630 - (22%)
• Similarity: 251/630 - (39%)
• Gaps: 158/630 - (25%)

  Fly    20 RGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQFS 83
            |.||:....|:..|.|..:.| :::...|....:.|...|:|:.:.:|:..:|:|.:...:||..
Human    32 RPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFAIGQRL 96

  Fly    84 SSGFIAAF-RLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSWHNR 147
            ..|.:..: .:.|..||:|..|:..:|...:||:..::..:.:|.|||:..||||
Human    97 RRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWS---------- 151

  Fly   148 TDEYPTLCHPTIYKQHENYTLGVEAPSRLYFDYIRQDYFNTDKRFDISRPLIGLFTLSWALIAII 212
              :.|.         :||.|..|:..:|    ....|||...:..:||..:....::.|.::..:
Human   152 --DCPL---------NENQTGYVDECAR----SSPVDYFWYRETLNISTSISDSGSIQWWMLLCL 201

  Fly   213 FYHFS----------EPAKFGKCIRYMVITTMVLVVVCF-VRFLFLPGSHKLLWMYITPNTKDFS 266
            ...:|          |..  ||.: |:..|...:|:..| :|.|.|.|:...:....|||..:.:
Human   202 ACAWSVLYMCTIRGIETT--GKAV-YITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELA 263

  Fly   267 EGIYSTFIMA----LQAFGAGWGSVIALSSFNGFKTDIMSYSWIIS----FGQIFI-YIMFGLVS 322
            :.  .|::.|    ..:|...:|.:|:.||:|....:....|.|:|    |..::: .:::.::.
Human   264 QP--DTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIG 326

  Fly   323 FMLEQYYKDISDTIVFHRIMNFWV------------------------------------LFLSS 351
            |...|.|.|...|.:...|..|.:                                    .|||.
Human   327 FRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSE 391

  Fly   352 A------------SALNTLGWPNLWTFIYYSMLLLASLTVIATQLFTVLQSLFDEFEKLK----E 400
            |            .|:..:....||:.:::.||....|    :.:|..::.:....:.|:    :
Human   392 AVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGL----SSMFGNMEGVVVPLQDLRVIPPK 452

  Fly   401 RKQEVTFGIIC-GLAICSFFFCTEHGSFYFAILGIDVILAHSLLHLLL----LLVVLWIYGQKRF 460
            ..:||..|:|| |..:..|.|....|.::.::|.   ..|.|:..|::    :..|:::||..||
Human   453 WPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLD---SYAGSIPLLIIAFCEMFSVVYVYGVDRF 514

  Fly   461 QRDIEFMLG-QPFASWKVFILRYTAPIVFLICMILGIIECIRVHFFFKEV--------------- 509
            .:|||||:| :|...|:| ..|..:|::.||         |.:.||..||
Human   515 NKDIEFMIGHKPNIFWQV-TWRVVSPLLMLI---------IFLFFFVVEVSQELTYSIWDPGYEE 569

  Fly   510 ------------FLVLGIILVVLPFLAIPGYGFYYL----RQSPG 538
                        ..|:.:|:..:|.|.||||..|.|    .|.||
Human   570 FPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPG 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	119/548 (22%)
SLC6A19	NP_001003841.1	SLC5-6-like_sbd	32..612	CDD:444915	137/626 (22%)