Protein Alignment CG33296 and Slc6a11

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_766478.1
• Gene: Slc6a11 / 243616
• MGIID: 95630
• Length: 627
• Species: Mus musculus
• Alignment Length: 642
• Identity: 132/642 - (20%)
• Similarity: 267/642 - (41%)
• Gaps: 140/642 - (21%)

  Fly     8 ASGTKPFSPDP--KRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYL 69
            |:||:......  :||.|....:::.:..|..:.| :::...|..:.|.|...::||.::.:...
Mouse    31 AAGTREARDKAVHERGHWNNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFLIPYVVFFICCG 95

  Fly    70 VPILVVHSFMGQFSSSGFIAAF-RLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPT 133
            :|:..:.:.:|||:|.|.|..: |:.|||:|:||.:..:.....:||.:.:|..:.:|.|.|...
Mouse    96 IPVFFLETALGQFTSEGGITCWRRVCPLFEGIGYATQVIEAHLNVYYIIILAWAIFYLSNCFTTE 160

  Fly   134 LPWSCEGLKSWH-NRTDEYPTL-----CHPTIYKQHENYTL---------------GVEAPSRLY 177
            |||:..| ..|: .:..|:..|     .|.::    :|.|.               |:|....|
Mouse   161 LPWATCG-HEWNTEKCVEFQKLNFSNYSHVSL----QNATSPVMEFWERRVLAISDGIEHIGNL- 219

  Fly   178 FDYIRQDYFNTDKRFDISRPLIGLFTLSWALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCFV 242
                         |::::..|:..:|:.:      |..:......||.:........:::::..:
Mouse   220 -------------RWELALCLLAAWTICY------FCIWKGTKSTGKVVYVTATFPYIMLLILLI 265

  Fly   243 RFLFLPGSHKLLWMYITPNTKDFSE---------GIYSTFIMALQAFGAGWGSVIALSSFNGFKT 298
            |.:.|||:.:.:..|:.|:....|:         .|:.::.:.|       |.:.||.|:|.:..
Mouse   266 RGVTLPGASEGIKFYLYPDLSRLSDPQVWVDAGTQIFFSYAICL-------GCLTALGSYNNYNN 323

  Fly   299 D-----IMSYSWIISFGQIFI--YIMFGLVSFMLEQYYKDISDTIVFHRIMNFWVLFLSSASALN 356
            :     ||  ...::.|..|:  :.:|.::.||..:....|::...    ....:.|::...|:.
Mouse   324 NCYRDCIM--LCCLNSGTSFVAGFAIFSVLGFMAYEQGVPIAEVAE----SGPGLAFIAYPKAVT 382

  Fly   357 TLGWPNLWTFIYYSMLLLASLTVIATQLFTVLQSLFDEFEKLKER--KQEVTFGIICGLAICSFF 419
            .:....||..:::.||:...|......:.:::.::.|.:.|:..|  ::|:   :|..|:|.|:|
Mouse   383 MMPLSPLWATLFFMMLIFLGLDSQFVCVESLVTAVVDMYPKVFRRGYRREL---LILALSIISYF 444

  Fly   420 ----FCTEHGSFYFAILGIDVILAHSLLHLLLLLVVL-------WIYGQKRFQRDIEFMLG-QPF 472
                ..||.|.:.|.:..     :::...:.||.|.:       |:||..||..:||.|:| :|.
Mouse   445 LGLVMLTEGGMYIFQLFD-----SYAASGMCLLFVAIFECVCIGWVYGSNRFYDNIEDMIGYRPL 504

  Fly   473 A----SWKVFILRYTAPIVFLICMILGIIECIRVHFFF---------KEVFLV------LGIILV 518
            :    .|||     ..|         ||  |..:..||         ..|:..      :|.::.
Mouse   505 SLIKWCWKV-----VTP---------GI--CAGIFIFFLVKYKPLKYNNVYTYPAWGYGIGWLMA 553

  Fly   519 VLPFLAIPGYGFYYLRQSPGTFLERLKRSCRPTDWYPVEMKHRQHYGDRVGNIEMTD 575
            :...|.||.:.|..|.::.||..|:|::...|:    .::|.|...|.....:.:.|
Mouse   554 LSSMLCIPLWIFIKLWKTEGTLPEKLQKLTVPS----ADLKMRGKLGASPRTVTVND 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	105/525 (20%)
Slc6a11	NP_766478.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36		3/4 (75%)
		SLC6sbd_GAT3	44..585	CDD:212077	124/602 (21%)