Protein Alignment CG33296 and Slc6a1

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_848818.1
• Gene: Slc6a1 / 232333
• MGIID: 95627
• Length: 599
• Species: Mus musculus
• Alignment Length: 576
• Identity: 151/576 - (26%)
• Similarity: 262/576 - (45%)
• Gaps: 83/576 - (14%)

  Fly    18 PKRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQ 81
            |.|..|:...|:|.:|.|.|:.| :::...|....|.|...::||||.::...||:.::...:||
Mouse    42 PDRDTWKGRFDFLMSCVGYAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFLLECSLGQ 106

  Fly    82 FSSSGFIAAFRLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPW-SCEGLKSWH 145
            ::|.|.:..::|||:|||:|..:..|:|...|||.:.::..:.:|.|||..|||| .|:  ..|:
Mouse   107 YTSIGGLGVWKLAPMFKGVGLAAAVLSFWLNIYYIVIISWAIYYLYNSFTTTLPWKQCD--NPWN 169

  Fly   146 NRTDEYPTLCHPTIYKQHENYTL-----GVEAPSRLYFDYIRQDYFNTDKRFDISRPLIGLFTLS 205
              ||.    |       ..||:|     ...|....:...:.|.....||...|..||.....::
Mouse   170 --TDR----C-------FSNYSLVNTTNMTSAVVEFWERNMHQMTDGLDKPGQIRWPLAITLAIA 221

  Fly   206 WALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYITPNTKDFSEGIY 270
            |.|  :.|..:......||.:.:......:::::.|.|.:.|||:.:.:..|||||.:..|:.
Mouse   222 WVL--VYFCIWKGVGWTGKVVYFSATYPYIMLIILFFRGVTLPGAKEGILFYITPNFRKLSDS-- 282

  Fly   271 STFIMALQ----AFGAGWGSVIALSSFNGFKTDIMSYSWII----SFGQIFI-YIMFGLVSFMLE 326
            ..::.|..    ::|.|.||:|||.|:|.|..::...|.|:    |...:|. :::|.:|.||..
Mouse   283 EVWLDAATQIFFSYGLGLGSLIALGSYNSFHNNVYRDSIIVCCINSCTSMFAGFVIFSIVGFMAH 347

  Fly   327 QYYKDISDTIVFHRIMNFWVLFLSSASALNTLGWPNLWTFIYYSMLLLASLTVIATQLFTV---L 388
            ...:.|:|...    ....:.||:...|:..|....||..:::||||:..   |.:|..||   :
Mouse   348 VTKRSIADVAA----SGPGLAFLAYPEAVTQLPISPLWAILFFSMLLMLG---IDSQFCTVEGFI 405

  Fly   389 QSLFDEFEKLKERKQEVTFGIICGLAICSFFF----CTEHGSFYFAILGIDVILAHSLLHLLLL- 448
            .:|.||:.:|...::|:....:|   |.|:..    .|:.|.:.|.:.........|||.|:..
Mouse   406 TALVDEYPRLLRNRRELFIAAVC---IVSYLIGLSNITQGGIYVFKLFDYYSASGMSLLFLVFFE 467

  Fly   449 -LVVLWIYGQKRFQRDIEFMLG-QPFASWKVFILRYTAPIVFLICMILGIIECIRVHFFFKEVFL 511
             :.:.|.||..||..:|:.|:| :|...||:....:| ||:     :.|:       |.|..|.:
Mouse   468 CVSISWFYGVNRFYDNIQEMVGSRPCIWWKLCWSFFT-PII-----VAGV-------FLFSAVQM 519

  Fly   512 V---------------LGIILVVLPFLAIPGYGFYYLRQSPGTFLERLKRSCRPTD 552
            .               :|.::.:...:.||||..|......|:..:||:...:|::
Mouse   520 TPLTMGSYVFPKWGQGVGWLMALSSMVLIPGYMAYMFLTLKGSLKQRLQVMIQPSE 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	134/494 (27%)
Slc6a1	NP_848818.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23
		SLC6sbd_GAT1	2..599	CDD:212075	151/576 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	577..599
		PDZ-binding	597..599