DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33296 and Slc6a13

DIOPT Version :9

Sequence 1:	NP_001285711.1	Gene:	CG33296 / 2768941	FlyBaseID:	FBgn0053296	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_006237280.2	Gene:	Slc6a13 / 171163	RGDID:	620788	Length:	608	Species:	Rattus norvegicus

Alignment Length:	608	Identity:	142/608 - (23%)
Similarity:	253/608 - (41%)	Gaps:	103/608 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 TKPFSP---------DPKRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYM 65
            |||..|         ..:|.:|....:::.:..|..:.| :::...|..:.|.|....:||.:::
  Rat    14 TKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFL 78

  Fly    66 VIYLVPILVVHSFMGQFSSSGFIAAFR-LAPLFK------GMGYVSIFLTFTTLIYYSMFVAIPL 123
            ....:|:..:.:.:||:::.|.|.|:| :.|:|:      |:||.|..:.....:||.:.:|..|
  Rat    79 FTCGIPVFFLETALGQYTNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLNVYYIVVLAWAL 143

  Fly   124 LFLINSFRPTLPW-SCEGLKSWHNRTDEYPTLCHPTIYKQHENYTLGV---EAPSRLYFDYIRQD 184
            .:|.:||...||| ||.  ..|:...      |   :..|..|.:|.|   .|.|.:...:.|
  Rat   144 FYLFSSFTTDLPWGSCS--HEWNTEN------C---VEFQKTNNSLNVTSENATSPVIEFWER-- 195

  Fly   185 YFNTDKRFDISRPLIGLFTLSWALIA------IIFYH--FSEPAKFGKCIRYMVITTMVLVVVCF 241
                 :...||..:..|.:|.|.|:.      ||.|.  :......||.:.:......:::||..
  Rat   196 -----RVLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLVVLL 255

  Fly   242 VRFLFLPGSHKLLWMYITPNT---------KDFSEGIYSTFIMALQAFGAGWGSVIALSSFNGFK 297
            :|.:.|||:.:.:..|:.||.         .|....|:.:|.:.|       |.:.||.|:|.:.
  Rat   256 IRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICL-------GCLTALGSYNKYH 313

  Fly   298 TDI-----------MSYSWIISFGQIFIYIMFGLVSFMLEQYYKDISDTIVFHRIMNFWVLFLSS 351
            .:.           .|.|::..|.      :|.::.||.::....||:...    ....:.|::.
  Rat   314 NNCYRDCVALCILNSSTSFVAGFA------IFSILGFMSQEQGVPISEVAE----SGPGLAFIAY 368

  Fly   352 ASALNTLGWPNLWTFIYYSMLLLASLT---VIATQLFTVLQSLFDEFEKLKERKQEVTFGIICGL 413
            ..|:..|.:..||...::.|::|..|.   |....|.|.|..::....:.|.|::.    :|..:
  Rat   369 PRAVVMLPFSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREI----LILIV 429

  Fly   414 AICSFF----FCTEHGSFYFAILGIDVILAHSLLHLLLL--LVVLWIYGQKRFQRDIEFMLG-QP 471
            ::.|||    ..||.|.:.|.:..........||.:.:.  |.|.|:||..||..:||.|:| :|
  Rat   430 SVVSFFIGLIMLTEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKP 494

  Fly   472 FASWKVFILRYTAPIVFLICMILGIIECIRVHFFFKEVFL----VLGIILVVLPFLAIPGYGFYY 532
            :...|...|.:| |.|.|...:..:|:...:.:..|..:.    .||.:|.:...:.||.:..|.
  Rat   495 WPLIKYCWLFFT-PAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSIYK 558

  Fly   533 LRQSPGTFLERLKRSCRPTDWYP 555
            ||...|...|||::...|.:..|
  Rat   559 LRTLKGPLRERLRQLVCPAEDLP 581

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	120/518 (23%)
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:382020	137/588 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000