Protein Alignment CG33296 and Slc6a4

DIOPT Version :9

• Sequence 1: NP_001285711.1
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_034614.2
• Gene: Slc6a4 / 15567
• MGIID: 96285
• Length: 630
• Species: Mus musculus
• Alignment Length: 590
• Identity: 150/590 - (25%)
• Similarity: 263/590 - (44%)
• Gaps: 75/590 - (12%)

  Fly    19 KRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQF 82
            :|..|.|..|:|.:..|.|:.| :|:...|..:.|.|...:|||.:..:...:|:..:...:||:
Mouse    78 ERETWGKKMDFLLSVIGYAVDLGNIWRFPYICYQNGGGAFLLPYTIMAIFGGIPLFYMELALGQY 142

  Fly    83 SSSGFIAAF-RLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPW-SCEGLKSWH 145
            ..:|.|:.: ::.|:|||:||....:.|....||:..:|..|.:||:||...||| ||:  .||:
Mouse   143 HRNGCISIWKKICPIFKGIGYAICIIAFYIASYYNTIIAWALYYLISSFTDQLPWTSCK--NSWN 205

  Fly   146 NRTDEYPTLCHPTIYKQHEN--YTLGVEAPS-RLYFDYIRQDYFNTDKRFDISRPLIGLFTLSWA 207
            ...      |  |.|...:|  :||...:|: ..|..::.|        ...|:.|..|.|:||.
Mouse   206 TGN------C--TNYFAQDNITWTLHSTSPAEEFYLRHVLQ--------IHQSKGLQDLGTISWQ 254

  Fly   208 L-------IAIIFYHFSEPAK-FGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYITPNTKD 264
            |       ..||::...:..| .||.:........:::.|..||...|||:.:.:..|:.||.:.
Mouse   255 LALCIMLIFTIIYFSIWKGVKTSGKVVWVTATFPYIVLSVLLVRGATLPGAWRGVVFYLKPNWQK 319

  Fly   265 FSE-GIYSTFIMALQAF---GAGWGSVIALSSFNGFKTDIMSYSWIISFGQI---FI--YIMFGL 320
            ..| |::..  .|.|.|   |.|:|.::|.:|:|.|..:....:.:.|....   |:  :::|.:
Mouse   320 LLETGVWVD--AAAQIFFSLGPGFGVLLAFASYNKFNNNCYQDALVTSVVNCMTSFVSGFVIFTV 382

  Fly   321 VSFMLEQYYKDISDTIVFHRIMNFWVLFLSSASALNTLGWPNLWTFIYYSMLLLASLTVIATQLF 385
            :.:|.|...:|:|:..   :.....:||::.|.|:..:.....:..|::.||:...|......|.
Mouse   383 LGYMAEMRNEDVSEVA---KDAGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGLDSTFAGLE 444

  Fly   386 TVLQSLFDEFEKLKERKQEVTFGIICGLAICSFFFCTEHGSFYFAILGIDVILAHSLLHLLLL-- 448
            .|:.::.|||..:..:::|....|:....|.........|..|...|..:.....::|.:.|:
Mouse   445 GVITAVLDEFPHIWAKRREWFVLIVVITCILGSLLTLTSGGAYVVTLLEEYATGPAVLTVALIEA 509

  Fly   449 LVVLWIYGQKRFQRDIEFMLG-QPFASWKV--------FILRYTAPIVFLICMILGIIECIRV-H 503
            :||.|.||..:|..|::.||| .|...|::        |:|       |:||..|.....:|: .
Mouse   510 VVVSWFYGITQFCSDVKEMLGFSPGWFWRICWVAISPLFLL-------FIICSFLMSPPQLRLFQ 567

  Fly   504 FFFKEVFLVLGIILVVLPFLAIPGYGFYYLRQSPGTFLERLKRSCRPTDWYPVEMKHRQHYGDRV 568
            :.:....::||..:.....:.||.|..|.|..:|||..||:.:|..|..  |.|:.        .
Mouse   568 YNYPHWSIILGYCIGTSSVICIPIYIIYRLISTPGTLKERIIKSITPET--PTEIP--------C 622

  Fly   569 GNIEM 573
            |:|.|
Mouse   623 GDIRM 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	127/502 (25%)
Slc6a4	NP_034614.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..63
		5HT_transport_N	24..64	CDD:281488
		SLC6sbd_SERT	79..615	CDD:271399	144/565 (25%)
		Interaction with RAB4A. /evidence=ECO:0000250	616..624		2/17 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810