Protein Alignment CG33296 and Slc6a12

DIOPT Version :10

• Sequence 1: NP_995644.2
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_598422.2
• Gene: Slc6a12 / 14411
• MGIID: 95628
• Length: 628
• Species: Mus musculus
• Alignment Length: 594
• Identity: 126/594 - (21%)
• Similarity: 245/594 - (41%)
• Gaps: 107/594 - (18%)

  Fly    20 RGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQFS 83
            ||:|....:::.:..|..:.| :::...|..:.|.|....:|||::.....:|:..:...:||:|
Mouse    50 RGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFSCGIPVFFLEVALGQYS 114

  Fly    84 SSGFIAAFR-LAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPW-SCEGLKSWHN 146
            |.|.:.|:| :.||.:|:|..|:.:.....|||.:.:|..|.:|.:||...||| :|  ..||:.
Mouse   115 SQGSVTAWRKICPLLQGIGMASVVIESYLNIYYIIILAWALFYLFSSFTWELPWTTC--TNSWNT 177

  Fly   147 RTDEYPTLCHPTIYKQH---------ENYTLGVEAPSRLYFDYIRQDYFNTDKRFDISRPLIGLF 202
            .        |...:..|         ||:|    :|...:::         .:...|:..:..|.
Mouse   178 E--------HCVDFLNHSSARGVSSSENFT----SPVMEFWE---------RRVLGITSGIHDLG 221

  Fly   203 TLSW-----ALIAIIFYHF---SEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHKLLWMYIT 259
            :|.|     .|:|.|..:|   ......||.:.:......:::::..:|.:.|||:::.:..|:.
Mouse   222 SLRWELALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLIILLIRGVTLPGAYQGIVFYLK 286

  Fly   260 PNT---------KDFSEGIYSTFIMALQAFGAGWGSVIALSSFNGFKTDIMSYSWIISF---GQI 312
            |:.         .|....|:.:|.:.       .|.:.||.|:|.:..:....|..:.|   ...
Mouse   287 PDLLRLKDPQVWMDAGTQIFFSFAIC-------QGCLTALGSYNKYHNNCYRDSIALCFLNSATS 344

  Fly   313 FI--YIMFGLVSFMLEQYYKDISDTIVFHRIMNFWVLFLSSASALNTLGWPNLWTFIYYSMLL-- 373
            |:  :::|.::.||.::....||:...    ....:.|::...|:..:....||:.:::.|||
Mouse   345 FVAGFVVFSILGFMSQEQGIPISEVAE----SGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLLFL 405

  Fly   374 -LASLTVIATQLFTVLQSLFDEFEKLKERKQEVTFGIICGLAICSFFFCTEHGSF------YFAI 431
             |.|..|....|.|....:|.:..:...|::.:...|.....:......||.|.:      |:|.
Mouse   406 GLDSQFVCMECLVTASMDMFPQQLRKSGRRELLILAISVLCYLMGLLLVTEGGMYIFQLFDYYAS 470

  Fly   432 LGIDVILAHSLLHLLLLLVVLWIYGQKRFQRDIEFMLGQPFASWKVFILRYTAPIVFLICMILGI 496
            .||.::    .|.|..::.:.|:||..||..::|.|:|  :..|         |:|.:..:.|..
Mouse   471 SGICLL----FLSLFEVICIGWVYGADRFYDNVEDMIG--YRPW---------PLVKISWLFLTP 520

  Fly   497 IECIRVHFF---------FKEVFLV------LGIILVVLPFLAIPGYGFYYLRQSPGTFLERLKR 546
            ..|:...||         :..|::.      :|.:|.......:|.:......::.|:|.:||:|
Mouse   521 GLCLATFFFSLSKYTPLKYNNVYMYPSWGYSIGWLLAFSSMACVPLFIIITFLKTQGSFKKRLRR 585

  Fly   547 SCRPTDWYP 555
            ...|....|
Mouse   586 LITPDPSLP 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_995644.2	SLC5-6-like_sbd	27..496	CDD:271356	109/511 (21%)
Slc6a12	NP_598422.2	SLC5-6-like_sbd	49..589	CDD:444915	124/587 (21%)