Protein Alignment CG33296 and Slc6a8

DIOPT Version :9

• Sequence 1: NP_001285711.1
• Gene: CG33296 / 2768941
• FlyBaseID: FBgn0053296
• Length: 585
• Species: Drosophila melanogaster
• Sequence 2: NP_598748.1
• Gene: Slc6a8 / 102857
• MGIID: 2147834
• Length: 640
• Species: Mus musculus
• Alignment Length: 633
• Identity: 151/633 - (23%)
• Similarity: 250/633 - (39%)
• Gaps: 133/633 - (21%)

  Fly    18 PKRGKWEKPTDYLFACFGLALKL-DIFEVSYWFFFNIGFVGMLPYFLYMVIYLVPILVVHSFMGQ 81
            |.|..|.:..|::.:|.|.|:.| :::...|..:.|.|.|.::||.|..::..:||..:...:||
Mouse    50 PPRETWTRQMDFIMSCVGFAVGLGNVWRFPYLCYKNGGGVFLIPYVLIALVGGIPIFFLEISLGQ 114

  Fly    82 FSSSGFIAAFRLAPLFKGMGYVSIFLTFTTLIYYSMFVAIPLLFLINSFRPTLPWSCEGLKSWH- 145
            |..:|.|..:.:.|||||:||.|:.:.|....||.|.:|....:|:.||..||||:..| .:|:
Mouse   115 FMKAGSINVWNICPLFKGLGYASMVIVFYCNTYYIMVLAWGFYYLVKSFTTTLPWATCG-HTWNT 178

  Fly   146 ------------------NRT-DEYPTLCHPTIYKQHENYTL----GVEAPSRLYFDYIRQDYFN 187
                              |.| |:......|.| :..||..|    |:|.|..|
Mouse   179 PDCVEIFRHEDCANASLANLTCDQLADRRSPVI-EFWENKVLRLSTGLEVPGAL----------- 231

  Fly   188 TDKRFDISRPLIGLFTLSWALIAIIFYHFSEPAKFGKCIRYMVITTMVLVVVCFVRFLFLPGSHK 252
               .::::..|:.    .|.|  :.|..:......||.:.:......|::||..||.:.|||:..
Mouse   232 ---NWEVTLCLLA----CWVL--VYFCVWKGVKSTGKIVYFTATFPYVVLVVLLVRGVLLPGALD 287

  Fly   253 LLWMYITPNTKDFSE-GIYSTFIMA----LQAFGAGWGSVIALSSFNGFKTDIMSYSWI---ISF 309
            .:..|:.|   |:|: |....:|.|    ..::..|.|::.||.|:|.|..:....:.|   |:.
Mouse   288 GIIYYLKP---DWSKLGSPQVWIDAGTQIFFSYAIGLGALTALGSYNRFNNNCYKDAIILALINS 349

  Fly   310 GQIFI--YIMFGLVSFMLEQYYKDISDTIVFHRIMNFWVLFLSSASALNTLGWPN---------L 363
            |..|.  :::|.::.||..:....||..             ..|...|..:.:|.         |
Mouse   350 GTSFFAGFVVFSILGFMATEQGVHISKV-------------AESGPGLAFIAYPRAVTLMPVAPL 401

  Fly   364 WTFIYYSMLLLASLTV-------IATQLFTVL-QSLFDEFEKLKERKQEVTFGIICGLA-ICSFF 419
            |..:::.||||..|..       ..|.|..:| .|.:..|::      |::..:.|.|. :....
Mouse   402 WAALFFFMLLLLGLDSQFVGVEGFITGLLDLLPASYYFRFQR------EISVALCCALCFVIDLS 460

  Fly   420 FCTE-----HGSFYFAILGIDVILAHSLLHLLL--LLVVLWIYGQKRFQRDIEFMLGQPFASWKV 477
            ..|:     .|.:.|.:.........:||....  .:||.|:||..||..||..|:|.....|..
Mouse   461 MVTDVSGGKGGMYVFQLFDYYSASGTTLLWQAFWECVVVAWVYGADRFMDDIACMIGYRPCPWMK 525

  Fly   478 FILRYTAPIVFLICMILGIIECIRVHFFFKEVFL----------------VLGIILVVLPFLAIP 526
            :...:..|   |:||  ||       |.|..|:.                .:|....:...|.:|
Mouse   526 WCWSFFTP---LVCM--GI-------FIFNIVYYEPLVYNNTYVYPWWGEAMGWAFALSSMLCVP 578

  Fly   527 GYGFYYLRQSPGTFLERLKRSCRPTDWYPVEMKHRQHYGDRVGNIEMT 574
            .:....|.::.||..||.:...:|. |....:::|....|..|...:|
Mouse   579 LHLLGCLLRAKGTMAERWQHLTQPI-WGLHHLEYRAQDADVRGLTTLT 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33296	NP_001285711.1	SLC5-6-like_sbd	27..496	CDD:271356	129/528 (24%)
Slc6a8	NP_598748.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		SLC6sbd_CT1	52..626	CDD:271397	150/631 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000