Protein Alignment Pp2A-29B and ppp2r1bb

DIOPT Version :10

• Sequence 1: NP_001245944.1
• Gene: Pp2A-29B / 2768940
• FlyBaseID: FBgn0260439
• Length: 650
• Species: Drosophila melanogaster
• Sequence 2: NP_001005590.1
• Gene: ppp2r1bb / 449548
• ZFINID: ZDB-GENE-040927-20
• Length: 589
• Species: Danio rerio
• Alignment Length: 581
• Identity: 434/581 - (74%)
• Similarity: 499/581 - (85%)
• Gaps: 0/581 - (0%)

  Fly     9 DDSLYPIAVLIDELKNEDVQLRLNSIKKLSTIALALGEERTRSELIPFLTETIYDEDEVLLALAD 73
            ||||||||||||||:||||||||||||||||||||||.||||:||:||||:|||||||||||||:
Zfish     7 DDSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVERTRTELLPFLTDTIYDEDEVLLALAE 71

  Fly    74 QLGNFTSLVGGPEFAMYLIPPLESLATVEETVVRDKAVESLRTVAAEHSAQDLEIHVVPTLQRLV 138
            |||:||.|||||||...|:|||||||||||||||||||:|||.::.|||..|||:|.||.::||.
Zfish    72 QLGSFTVLVGGPEFVHCLLPPLESLATVEETVVRDKAVDSLRKISQEHSPVDLEVHFVPLVKRLA 136

  Fly   139 SGDWFTSRTSACGLFSVCYPRVTQPVKAELRANFRKLCQDETPMVRRAAANKLGEFAKVVETEYL 203
            ||||||||||||||||||||||:..||||:|.:||.||.|:|||||||||:||||||||:|.:|:
Zfish   137 SGDWFTSRTSACGLFSVCYPRVSSTVKAEIRQHFRTLCSDDTPMVRRAAASKLGEFAKVLELDYV 201

  Fly   204 KSDLIPNFVQLAQDDQDSVRLLAVEACVSIAQLLPQDDVEHLVLPTLRQCASDSSWRVRYMVAEK 268
            |||:||.|..||.|:|||||||||||.||||.||||:|:|.||:|||||.|.|.|||||||||:|
Zfish   202 KSDIIPLFTALASDEQDSVRLLAVEAGVSIATLLPQEDLEALVMPTLRQAAEDKSWRVRYMVADK 266

  Fly   269 FVDLQKAVGPEITRVDLVPAFQYLLKDAEAEVRAAVATKVKDFCANLDKVNQVQIILSSILPYVR 333
            |.:||||||||||:.|||||||.||||.|||||||.|.|||.||.||.:.::..||::.|||.|:
Zfish   267 FSELQKAVGPEITKNDLVPAFQNLLKDCEAEVRAAAANKVKVFCENLPEDSRETIIMTHILPCVK 331

  Fly   334 DLVSDPNPHVKSALASVIMGLSPMLGAYQTVEQLLPLFLIQLKDECPEVRLNIISNLDCVNDVIG 398
            :||||.|.||||||||||||||.:||...|||.||||||.|||||||||||||||||||||:|||
Zfish   332 ELVSDTNQHVKSALASVIMGLSTILGKDNTVEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIG 396

  Fly   399 IQQLSQSLLPAIVELAEDSKWRVRLAIIEYMPALAGQLGQEFFDQKLRGLCMGWLNDHVYAIREA 463
            |:||||||||||||||||:|||||||||||||.||||||.||||:||..|||.||.|||||||||
Zfish   397 IRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLIDHVYAIREA 461

  Fly   464 ATLNMKKLVEQFGAPWAEQAIIPMILVMSRNKNYLHRMTCLFCLNVLAEVCGTDITTKLLLPTVL 528
            ||.|:.||||:|||.||:..|:|.:|.|:.:.|||||||.|||:|.|:|.||.:||||.:||.||
Zfish   462 ATCNLMKLVEKFGAEWAQNTIVPKVLGMANDSNYLHRMTTLFCINALSEACGQEITTKHMLPVVL 526

  Fly   529 LLAADPVANVRFNVAKTLQKISPFLEASVIDAQVKPTLDKLNTDTDVDVKHFAAQAIAGIA 589
            .::.|.||||||||||:||||.|.||:|.:.|:|||.|:||:||.|:|||:||.:||:.:|
Zfish   527 KMSTDQVANVRFNVAKSLQKIGPVLESSALQAEVKPVLEKLSTDQDMDVKYFALEAISVLA 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pp2A-29B	NP_001245944.1	HEAT repeat	15..39	CDD:293787	22/23 (96%)
		HEAT repeat	53..80	CDD:293787	22/26 (85%)
		HEAT repeat	90..120	CDD:293787	23/29 (79%)
		HEAT repeat	129..154	CDD:293787	19/24 (79%)
		HEAT repeat	165..194	CDD:293787	21/28 (75%)
		HEAT_2	175..267	CDD:433376	69/91 (76%)
		HEAT repeat	206..232	CDD:293787	18/25 (72%)
		HEAT repeat	247..271	CDD:293787	18/23 (78%)
		HEAT repeat	285..313	CDD:293787	22/27 (81%)
		HEAT	<327..427	CDD:441023	83/99 (84%)
		HEAT repeat	327..357	CDD:293787	23/29 (79%)
		HEAT repeat	366..392	CDD:293787	23/25 (92%)
		HEAT repeat	403..432	CDD:293787	27/28 (96%)
		HEAT repeat	444..470	CDD:293787	19/25 (76%)
		HEAT repeat	481..510	CDD:293787	15/28 (54%)
		HEAT repeat	520..546	CDD:293787	17/25 (68%)
ppp2r1bb	NP_001005590.1	HEAT repeat	13..37	CDD:293787	22/23 (96%)
		HEAT repeat	51..78	CDD:293787	22/26 (85%)
		HEAT repeat	88..118	CDD:293787	23/29 (79%)
		HEAT	104..264	CDD:441023	117/159 (74%)
		HEAT repeat	127..152	CDD:293787	19/24 (79%)
		HEAT repeat	163..192	CDD:293787	21/28 (75%)
		HEAT repeat	204..234	CDD:293787	22/29 (76%)
		HEAT	220..388	CDD:441023	125/167 (75%)
		HEAT repeat	245..269	CDD:293787	18/23 (78%)
		HEAT repeat	283..311	CDD:293787	22/27 (81%)
		HEAT repeat	325..355	CDD:293787	23/29 (79%)
		HEAT repeat	364..390	CDD:293787	23/25 (92%)
		HEAT repeat	401..430	CDD:293787	27/28 (96%)
		HEAT repeat	442..468	CDD:293787	19/25 (76%)
		HEAT repeat	479..508	CDD:293787	15/28 (54%)
		HEAT repeat	518..544	CDD:293787	17/25 (68%)
		HEAT repeat	559..585	CDD:293787	16/25 (64%)