DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33282 and ATR2

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_014006.1	Gene:	ATR2 / 855322	SGDID:	S000004892	Length:	540	Species:	Saccharomyces cerevisiae

Alignment Length:	495	Identity:	91/495 - (18%)
Similarity:	158/495 - (31%)	Gaps:	176/495 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LSPTLTKIQTADSPLDFEVNLAQISWLGSMLGLDSLCGNLTIAMLIERAGRKFCLYLMAGPYACI 102
            :|.|.:...|.|||..   :....|..|..|...:.|   .:|.|:.:||:...|        ||
Yeast    43 VSSTKSTQVTNDSPWQ---DPTYFSSFGKELMFIATC---MLAQLLNQAGQTHAL--------CI 93

  Fly   103 WILIYCASNVYYLYAARFLCGFTGGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGILAGYIL 167
            ..::..:.|......|..:..|...||                     |.:::|..||.:.|...
Yeast    94 MNVLSKSFNSEANNQAWLMASFPLAAG---------------------SFILISGRLGDIYGLKK 137

  Fly   168 STYLAYHVVPFLAIILPVAYFIANIMLPETAPYLLKKSQLAAAENSFRYYRNQRSAICEQTSKVN 232
            ...:.|.:|...:||                      |.|:...||..::...|:
Yeast   138 MLIVGYVIVIVWSII----------------------SGLSKYSNSDAFFITSRA---------- 170

  Fly   233 FEELRTAVLSQQTRNATPLSYKDLTTKPALKGFAASIVLSL-------GYQFSGVFSFINYMSD- 289
            |:.:..|.:...........||       :..|..:||:|.       |..|.|:|..:....|
Yeast   171 FQGVGIAFILPNIMGLVGHVYK-------VGSFRKNIVISFIGACAPTGGMFGGLFGGLIVTEDP 228

  Fly   290 -----IFKASG-------------------------SVVDVNTATIIIGLV---------QIVGV 315
                 :|.|.|                         |:....:|..||||:         .|||.
Yeast   229 NQWPWVFYAFGIATFLSLLMAWYSIPNNVPTNIHGLSMDWTGSALAIIGLILFNFVWNQAPIVGW 293

  Fly   316 YTSTILVDIV----------------------------GRRVLMLISTMGVGIGCIAFGCFTYLA 352
            ....|:|.::                            .|.::|::..:.:|.|......|.|::
Yeast   294 DKPYIIVLLIISVIFLVAFFVYESKYAEVPLLPRAMTKNRHMIMILLAVFLGWGSFGIWTFYYVS 358

  Fly   353 KIYDLSDFN--WLPLVLMIIICYVANIGLIGIFFLVLVELFPVKIRSLATSLSVIFLSLLVF--G 413
            ...:|..::  |......:.:.:    |.:..||:..      .|:.|..:|.:.| ||:.|  |
Yeast   359 FQLNLRHYSPVWTGGTYFVFVIF----GSMAAFFVAF------SIKRLGPALLLCF-SLMAFDAG 412

  Fly   414 TL--KLFPLMLHYWGISFTMW----------FSAASALLT 441
            ::  .:.|:...||.::|.|.          |.|:|.:|:
Yeast   413 SIMFSVLPVEQSYWKLNFAMQAILCFGMDLSFPASSIILS 452

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	91/495 (18%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	72/432 (17%)
ATR2	NP_014006.1	MFS_Amf1_MDR_like	74..519	CDD:341029	82/461 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900