DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33282 and HXT9

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_012316.1	Gene:	HXT9 / 853236	SGDID:	S000003755	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	522	Identity:	115/522 - (22%)
Similarity:	213/522 - (40%)	Gaps:	104/522 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KNSL----------LQQK--TRYQLLATVIVNIITFGHGVGVGW----------LSPTLTKIQTA 48
            ||||          |.||  :.|..:| ::..:|.|| |...||          ||..:.:....
Yeast    36 KNSLNLDATEPPIDLPQKPLSAYTTVA-ILCLMIAFG-GFIFGWDTGTISGFVNLSDFIRRFGQK 98

  Fly    49 DSPLDFEVNLAQISWLGSMLGLDSLCGNLTIAMLIERAGRKFCLYLMAGPYACIWILIYCAS-NV 112
            :....:.::..::..:.|:..:....|.:.::.:.:..||:..|..:...|. :.|||...| |.
Yeast    99 NDKGTYYLSKVRMGLIVSIFNIGCAIGGIVLSKVGDIYGRRIGLITVTAIYV-VGILIQITSINK 162

  Fly   113 YYLY-AARFLCGFTGGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGILAGYILSTY--LAYH 174
            :|.| ..|.:.|...|...::.|:.|||||...|||.|..:..|...:||..|| .:.|  ..||
Yeast   163 WYQYFIGRIISGLGVGGIAVLSPMLISEVAPKQIRGTLVQLYQLMCTMGIFLGY-CTNYGTKNYH 226

  Fly   175 VVPFLAIILPV-----AYFIANIM-LPETAPYLLKKSQLAAAENSFRYYRNQRSAICEQTSKVNF 233
            ......:.|.:     .:.::.:| :||:..||::..:...|:.|..  ::.:.::.:......:
Yeast   227 NATQWRVGLGLCFAWTTFMVSGMMFVPESPRYLIEVGKDEEAKRSLS--KSNKVSVDDPALLAEY 289

  Fly   234 EELRTAV-LSQQTRNATPLSYKDLTTKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSV 297
            :.::..: |.:...||:........||...:.....::.|| .|.:|...|..|.:.|||:.| :
Yeast   290 DTIKAGIELEKLAGNASWSELLSTKTKVFQRVLMGVMIQSL-QQLTGDNYFFYYGTTIFKSVG-L 352

  Fly   298 VDVNTATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFG------CFTYLAKI-- 354
            .|....:||||:|.....:.:...::..|||.            |:.:|      ||...|.:
Yeast   353 KDSFQTSIIIGVVNFFSSFIAVYTIERFGRRT------------CLLWGAASMLCCFAVFASVGV 405

  Fly   355 ----------YDLSD---FNWLPLVLMIII----------CYVANIGLIGIFFLVLVELFPVKIR 396
                      .|::.   .|.:.:..|..|          |||           ::.|.||::::
Yeast   406 TKLWPQGSSHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCYV-----------IVSETFPLRVK 459

  Fly   397 S----LATSLSVIFLSLLVFGTLKLFPLMLHYWGISFTMWFSAASALLTFFYFWLFLQETKGKSM 457
            |    :||:.:.::..|:.|.|..:...:..|:|..|     ....:..:||.:.|:.||||.::
Yeast   460 SRGMAIATAANWMWGFLISFFTPFITGAINFYYGYVF-----LGCLVFAYFYVFFFVPETKGLTL 519

  Fly   458 IE 459
            .|
Yeast   520 EE 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	100/482 (21%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	84/401 (21%)
HXT9	NP_012316.1	Sugar_tr	64..526	CDD:395036	106/493 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9181
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.830