DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG33282 and Slc2a8

DIOPT Version :10

Sequence 1:NP_001097067.1 Gene:CG33282 / 2768939 FlyBaseID:FBgn0053282 Length:460 Species:Drosophila melanogaster
Sequence 2:NP_445946.2 Gene:Slc2a8 / 85256 RGDID:620611 Length:478 Species:Rattus norvegicus


Alignment Length:465 Identity:115/465 - (24%)
Similarity:207/465 - (44%) Gaps:42/465 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 RYQLLATVIVNIITFGHGVGVGWLSPTLTKIQTADSPLDFEVNLAQISWLGSMLGLDSLCGNLTI 79
            |...|||....:.....|..:|:.||.:..::.. :|....:.....||.|:::.|.:..|.:..
  Rat    24 RRVFLATFAAALGPLSFGFALGYSSPAIPSLRRT-APPALRLGDTAASWFGAVVTLGAAAGGVLG 87

  Fly    80 AMLIERAGRKFCLYLMAGPYACIWILIYCASNVYYLYAARFLCGFTGGAGYLVVPIFISEVADSN 144
            ..|::|||||..|.|...|:...:.:|..|.:|:.|...|.|.|...|...||.|::|||:|...
  Rat    88 GWLLDRAGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPA 152

  Fly   145 IRGALTSMVMLSVDLGILAGYILSTYLAYHVVPFLAIILPVAYFIANIMLPETAPYLLKKSQLAA 209
            :||.|.|.|.|.|..|||..|:....|.:..:..|..:.|....:....:|||..:||.:.|...
  Rat   153 VRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCYMPETPRFLLTQHQYQE 217

  Fly   210 AENSFRYYRNQRSAICEQTSKVNFEELRTAVLSQQTRNATPLSYKDLTTKPALKGFAASIVLSLG 274
            |..:.|:.........|.......:..:.|:|.:..           ..||.:.|    |.|.:.
  Rat   218 AMAALRFLWGSEEGWEEPPVGAEHQGFQLAMLRRPG-----------VHKPLIIG----ICLMVF 267

  Fly   275 YQFSGVFSFINYMSDIFKASGSVVDVNTATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVG 339
            .|.|||.:.:.|.:.||: .....|.:.|::.:|::|::....:.:::|..||::|:.:|.:.:.
  Rat   268 QQLSGVNAIMFYANTIFE-EAKFKDSSLASVTVGIIQVLFTAVAALIMDRAGRKLLLALSGVIMV 331

  Fly   340 IGCIAFGCF-----------TYLAKIYDLS--------DFNWLPLVLMIIICYVANIGLIGIFFL 385
            ....|||.:           :::..:..:|        ...||.:..|.:......:|...|.:|
  Rat   332 FSMSAFGTYFKLTQSGPSNSSHVGLLVPISAEPADVHLGLAWLAVGSMCLFIAGFAVGWGPIPWL 396

  Fly   386 VLVELFPVKIRSLATSLSVI---FLSLLVFGTLKLFPLMLHYWGISFTMWFSAASALLTFFYFWL 447
            ::.|:||:.|:.:||.:.|:   |::.||.........:|..:|   ..|.:||..:|:..:...
  Rat   397 LMSEIFPLHIKGVATGVCVLTNWFMAFLVTKEFNSIMEILRPYG---AFWLTAAFCILSVLFTLT 458

  Fly   448 FLQETKGKSM 457
            |:.||||:::
  Rat   459 FVPETKGRTL 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG33282NP_001097067.1 MFS_GLUT6_8_Class3_like 18..459 CDD:340916 114/462 (25%)
Slc2a8NP_445946.2 Dileucine internalization motif. /evidence=ECO:0000269|PubMed:10671487 12..13
MFS 27..470 CDD:475125 114/462 (25%)
Blue background indicates that the domain is not in the aligned region.

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