DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33282 and RGT2

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_010143.1	Gene:	RGT2 / 851417	SGDID:	S000002297	Length:	763	Species:	Saccharomyces cerevisiae

Alignment Length:	495	Identity:	110/495 - (22%)
Similarity:	194/495 - (39%)	Gaps:	95/495 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 TVIVNIIT------FGHGVGVGWLSPTLTKIQTADSPLDFEVNLAQISWLGSMLGLDSLCGNLTI 79
            :|:|.|..      ||:..|:......:..::|..:|.......:||:.|.|.|.|.:..|.|..
Yeast    99 SVLVGIFVAVGGFLFGYDTGLINSITDMPYVKTYIAPNHSYFTTSQIAILVSFLSLGTFFGALIA 163

  Fly    80 AMLIERAGRKFCLYLMAGPYACIWILIYCAS-NVYYLYAARFLCGFTGGAGYLVVPIFISEVADS 143
            ..:.:..|||..:.........|...:..|| .:..|...|.:.|...|....|||::.:|.|..
Yeast   164 PYISDSYGRKPTIMFSTAVIFSIGNSLQVASGGLVLLIVGRVISGIGIGIISAVVPLYQAEAAQK 228

  Fly   144 NIRGALTSMVMLSVDLGILAGYILS--TY-----LAYHVVPFLAIILPVAYFIANIMLPETAPYL 201
            |:|||:.|....::.:|:|....:|  |:     .:|.:...|..:......:..|.|||:..|.
Yeast   229 NLRGAIISSYQWAITIGLLVSSAVSQGTHSKNGPSSYRIPIGLQYVWSSILAVGMIFLPESPRYY 293

  Fly   202 LKKSQLAAAENSFRYYRN---QRSAICEQTSKV----NFEEL---RTAVLSQQTRNATPLSYKDL 256
            :.|.:|..|..|..:.|.   :...:.|:..::    ::|..   .|.:...:|....|.....:
Yeast   294 VLKDELNKAAKSLSFLRGLPIEDPRLLEELVEIKATYDYEASFGPSTLLDCFKTSENRPKQILRI 358

  Fly   257 TTKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSVVD-----------VNTATIIIGLV 310
            .|..|::.|         .|.||:.....|..:.|..:|  ||           ||.|      .
Yeast   359 FTGIAIQAF---------QQASGINFIFYYGVNFFNNTG--VDNSYLVSFISYAVNVA------F 406

  Fly   311 QIVGVYTSTILVDIVGRR-------VLMLISTMGVGIGCIAFGCFTYLAKIYDLSDFNWLPLVLM 368
            .|.|:|    |||.:|||       |:|.|:.:.:.|..::.|.....:||       .:..:.:
Yeast   407 SIPGMY----LVDRIGRRPVLLAGGVIMAIANLVIAIVGVSEGKTVVASKI-------MIAFICL 460

  Fly   369 IIICYVANIGLIGIFFLVLVELFPVKIRSLATSLS------VIFLSLLV--------FGTLKLFP 419
            .|..:.|..|  |:.::|..||:|:.:||..|::.      |.|...|:        ..|..:.|
Yeast   461 FIAAFSATWG--GVVWVVSAELYPLGVRSKCTAICAAANWLVNFTCALITPYIVDVGSHTSSMGP 523

  Fly   420 LMLHYWGISFTMWFSAASALLTFFYFWLFLQETKGKSMIE 459
            .:...||     ..:..:.::.:|..:    ||:|.::.|
Yeast   524 KIFFIWG-----GLNVVAVIVVYFAVY----ETRGLTLEE 554

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	106/482 (22%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	92/397 (23%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	110/495 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342446
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9181
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.840