DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33282 and YDL199C

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_010082.1	Gene:	YDL199C / 851328	SGDID:	S000002358	Length:	687	Species:	Saccharomyces cerevisiae

Alignment Length:	515	Identity:	114/515 - (22%)
Similarity:	201/515 - (39%)	Gaps:	116/515 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 NSLLQQKTRY--QLLATVIVN---IITFGHGVGVGWLSPTLTKIQ-------TADSPLDFEVNLA 59
            :.|..:|.|:  ::|.|..::   :::...|:..|.:|..:..:.       ...|||.   |:.
Yeast   105 SQLRSKKKRHSSRVLRTSFISFVVLVSSLSGLDQGLISGNVMTLSFQKYFHYPLTSPLG---NIV 166

  Fly    60 QISWLGSMLGLDSLCGNLTIAMLIERAGRKFCLYLMAGPYACIWILIYCASNVYYLYAARFLCGF 124
            .|..||:.:.  ||   ...:.::|...||..|.:....|:...|:...|.|.:.|...|||.|.
Yeast   167 SIVNLGAFMA--SL---FVYSGILEPCSRKKMLQISTMIYSLGAIVQVLALNQWCLLLGRFLLGV 226

  Fly   125 TGGAGYLVVPIFISEVADSNIR-------GALTSMVMLSVD---------LGILAGYILSTYLAY 173
            ..|..:.:|.|:..|.....||       ..::|::..|..         ||....|.|||::|
Yeast   227 GMGFAFSMVIIYQFEFPLPCIRKRTLISIQCVSSVIAYSFGIWINCAFRYLGFAWRYPLSTHVA- 290

  Fly   174 HVVPFLAIILPVAYFIANIMLPETAPYLLKKSQ----LAAAENSF---RYYRNQRSAICEQTSKV 231
                 |.|||.:..|   .::.|:..:|||:..    |....|.|   .:..||        :::
Yeast   291 -----LGIILNLMSF---YLILESPSWLLKQKNDVEALVLISNVFDDGNFEENQ--------TQL 339

  Fly   232 NFEELRTAVL--SQQTRNATPLSYKDLTTKPALKGFAASIVLSLGYQF----SGVFSFINYMSDI 290
            .|..|:..:|  |...:|:.|.:|       .||.|::.|.|.:|:|.    :||.:|:.|...|
Yeast   340 KFRVLKRDILLKSHLQKNSYPYAY-------ILKDFSSIIKLLIGFQLLTRTNGVDAFLYYSPLI 397

  Fly   291 FKASGSVVDVNTATIIIGLVQIVGVYTSTIL--VDIVGRR------VLMLISTMGVGIGCIAFGC 347
            .:..|.  ....:..:.||..:  :|:..||  |.:|.|:      ||:              |.
Yeast   398 LQQMGR--GERKSIYLTGLNAL--IYSIVILAYVPLVLRKRKEKTNVLL--------------GS 444

  Fly   348 FTYLAKIYDLSDFNWLP-------LVLMIIICYVANIGLIGIFFLVLVELFPVKIRSLATSLSVI 405
            ....|.::.:|..:|.|       .:|..:..:...|....|.:::.:||.|     ..:...||
Yeast   445 IVMCALLFTISFTDWFPKSTTRYISILFAVFLFTHFISWDSIGWVMTIELLP-----HLSQAPVI 504

  Fly   406 FLSLLVFGTLKLF-----PLMLHYWGISFTMWFSAASALLTFFYFWLFLQETKGKSMIED 460
            .|....:...|.|     |:::......|.:..|.:|.:...|...:|..||:.:.:..|
Yeast   505 LLVSNFYWIFKWFVSLITPILIDRLSWKFYLIPSLSSFISIIFVLKIFPIETRDERLDSD 564

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	106/485 (22%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	92/399 (23%)
YDL199C	NP_010082.1	MFS	122..566	CDD:421695	109/498 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900