DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33282 and slc2a1

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001072458.1	Gene:	slc2a1 / 779913	XenbaseID:	XB-GENE-5755357	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	475	Identity:	119/475 - (25%)
Similarity:	206/475 - (43%)	Gaps:	62/475 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LATVIVNIITFGHGVGV---------GWLSPTLTKIQTADSPLDFEVNLAQISWLG-SMLGLDSL 73
            :.|.::..:.||:..||         |:.:.|.  ::..:.|:. |..|..:..|. ::..:..:
Frog    15 VCTAVIGSLQFGYNTGVINAPQEVIEGFYNATW--LERYNEPIP-ESTLTSLWSLSVAIFSVGGM 76

  Fly    74 CGNLTIAMLIERAGRKFCLYLMAGPYACIWILIY----CASNVYYLYAARFL----CGFTGGAGY 130
            .|:.::.:.:.|.||:..: |||...|.:..::.    .|.:...|...||:    ||.|.|
Frog    77 VGSFSVGLFVNRFGRRNSM-LMANVLAFLAAILMGFSKLAVSFEMLIIGRFVVGLYCGLTTG--- 137

  Fly   131 LVVPIFISEVADSNIRGALTSMVMLSVDLGILAGYI--LSTYLAYHVV-PFLAIILPVAYFIANI 192
             .||:::.||:.:::||||.::..|.|.:|||...|  |...:....: |||...:.:...:..|
Frog   138 -FVPMYVGEVSPTSLRGALGTLHQLGVVVGILIAQIFGLKPIMGNDSLWPFLLGCIFIPAILQCI 201

  Fly   193 ML---PETAPYLL-KKSQLAAAENSFRYYRNQRSAICEQTSKVNFEELRTAVLSQQTRNATPLSY 253
            ||   ||:..:|| .:::...|::..:..|.        |:.|:.:.......|:|......::.
Frog   202 MLPFCPESPRFLLINRNEEDKAKSVLKKLRG--------TTDVSSDLQEMKEESRQMMREKKVTI 258

  Fly   254 KDLTTKPALKG--FAASIVLSLGYQFSGVFSFINYMSDIFKASGSVVDVNTATIIIGLVQIVGVY 316
            .:|...|..:.  |.| |:|.|..|.||:.:...|.:.||: ...|.....|||..|:|......
Frog   259 LELFRSPLYRQPMFIA-IILQLSQQLSGINAVFYYSTMIFQ-KAQVEQPVYATIGAGIVNTAFTV 321

  Fly   317 TSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLAKIYDLSDFNWLPLVLMIIICYVANIGLIG 381
            .|..:|:..|||.|.||...|:.:..|..  ...||.:..:...::|.:|.:........||...
Frog   322 VSLFVVERAGRRTLHLIGLGGMAVCAILM--TIALALLDSVGGMSYLSIVAIFGFVAFFEIGPGP 384

  Fly   382 IFFLVLVELFPVKIRSLATSLSVIFLS------LLVFGTLKLFPLMLHYWGISFTMWFSAASALL 440
            |.:.::.|||....|..|  ::|..||      ::..|...:..|...|..|.||:      .||
Frog   385 IPWFIVAELFSQGPRPAA--IAVAGLSNWTSNFIVGMGFQYVEQLCGAYVFIIFTV------LLL 441

  Fly   441 TFFYFWLF-LQETKGKSMIE 459
            .||.|..| :.||||::..|
Frog   442 IFFVFTYFKVPETKGRTFDE 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	113/459 (25%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	94/379 (25%)
slc2a1	NP_001072458.1	MFS_GLUT_Class1	13..457	CDD:340989	117/469 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.000