Protein Alignment CG33282 and SLC2A4

DIOPT Version :10

• Sequence 1: NP_001097067.1
• Gene: CG33282 / 2768939
• FlyBaseID: FBgn0053282
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_001033.1
• Gene: SLC2A4 / 6517
• HGNCID: 11009
• Length: 509
• Species: Homo sapiens
• Alignment Length: 501
• Identity: 118/501 - (23%)
• Similarity: 196/501 - (39%)
• Gaps: 97/501 - (19%)

  Fly    11 QQKTRYQLLATV---IVNIITFGHGVGV--------------GWLSPTLTKIQTADSPLDFEVNL 58
            ||:....|:..|   ::..:.||:.:||              .||..     |..:.|.......
Human    17 QQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGR-----QGPEGPSSIPPGT 76

  Fly    59 AQISWLGS--MLGLDSLCGNLTIAMLIERAGRKFCLY---LMAGPYACIWILIYCASNVYYLYAA 118
            ....|..|  :..:..:..:..|.::.:..|||..:.   ::|.....:..|...|::...|...
Human    77 LTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGSLMGLANAAASYEMLILG 141

  Fly   119 RFLCGFTGGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGILAGYILS------------TYL 171
            |||.|...|....:||:::.|:|.:::||||.::..|::.:|||...:|.            ..|
Human   142 RFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESLLGTASLWPLLL 206

  Fly   172 AYHVVPFL--AIILPVAYFIANIMLPETAPYLLKKSQL-AAAENSFRYYRNQRSAICEQTSKVNF 233
            ...|:|.|  .::||        ..||:..||.....| ..|..|.:     |.......|.| .
Human   207 GLTVLPALLQLVLLP--------FCPESPRYLYIIQNLEGPARKSLK-----RLTGWADVSGV-L 257

  Fly   234 EELRTAVLSQQTRNATPLSYKDLT-TKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSV 297
            .||:..  .::.....|||...|. ::...:....::||.|..|.||:.:...|.:.||:.:| |
Human   258 AELKDE--KRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQLSGINAVFYYSTSIFETAG-V 319

  Fly   298 VDVNTATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLAKIYDLSDFNW 362
            .....|||..|:|..|....|.:||:..|||.|.|:...|:   |   ||...:.
Human   320 GQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM---C---GCAILMT---------- 368

  Fly   363 LPLVL------MIIICYVANIGLIGIF--------FLVLVELFPVKIRSLATSLSVI--FLSLLV 411
            :.|:|      |..:..||..|.:..|        :.::.|||....|..|.:::..  :.|..:
Human   369 VALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFI 433

  Fly   412 FGTLKLFPLMLHYWGISFTMWFSAASALLTFFYF-WLFLQETKGKS 456
            .|  ..|..:....|....:.|  |..||.||.| :|.:.||:|::
Human   434 IG--MGFQYVAEAMGPYVFLLF--AVLLLGFFIFTFLRVPETRGRT 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS_GLUT6_8_Class3_like	18..459	CDD:340916	116/494 (23%)
SLC2A4	NP_001033.1	Interaction with SRFBP1. /evidence=ECO:0000269|PubMed:16647043	7..13
		MFS_GLUT_Class1	26..474	CDD:340989	114/489 (23%)
		Dileucine internalization motif. /evidence=ECO:0000269|PubMed:8300557	489..490