Protein Alignment CG33282 and SLC2A3

DIOPT Version :9

• Sequence 1: NP_001097067.1
• Gene: CG33282 / 2768939
• FlyBaseID: FBgn0053282
• Length: 460
• Species: Drosophila melanogaster
• Sequence 2: NP_008862.1
• Gene: SLC2A3 / 6515
• HGNCID: 11007
• Length: 496
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 133/498 - (26%)
• Similarity: 218/498 - (43%)
• Gaps: 90/498 - (18%)

  Fly    12 QKTRYQLLATVIVNII---TFGHGVGV---------GWLSPTLTKIQTADSPLDFEVNLAQISWL 64
            ||....|:..:.|..|   .||:..||         .:::.|||  ...::| ..||.|..:..|
Human     4 QKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLT--DKGNAP-PSEVLLTSLWSL 65

  Fly    65 G-SMLGLDSLCGNLTIAMLIERAGRK---FCLYLMAGPYACIWILIYCASNVYYLYAARFLCGFT 125
            . ::..:..:.|:.::.:.:.|.||:   ..:.|:|....|...|...|.:|..|...|.:.|..
Human    66 SVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLF 130

  Fly   126 GGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGILAG------YILST------YLAYHVVPF 178
            .|.....||::|.|::.:.:|||..::..|.:.:|||..      :||.:      .|.:.::|.
Human   131 CGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPA 195

  Fly   179 L--AIILPVAYFIANIMLPETAPYLL--KKSQLAAAENSFRYYRNQRSAICEQTSKVNFEELRTA 239
            :  :..||        ..||:..:||  :|.:..|.:...|.:..|  .:.:...::..|..|.:
Human   196 ILQSAALP--------FCPESPRFLLINRKEEENAKQILQRLWGTQ--DVSQDIQEMKDESARMS 250

  Fly   240 VLSQQTRNATPL------SYKDLTTKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSVV 298
                |.:..|.|      ||:    :|.:    .||||.|..|.||:.:...|.:.|||.:| |.
Human   251 ----QEKQVTVLELFRVSSYR----QPII----ISIVLQLSQQLSGINAVFYYSTGIFKDAG-VQ 302

  Fly   299 DVNTATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLAKIYDLSD-FNW 362
            :...|||..|:|..:....|..||:..|||.|.:|     |:|.:|| |.|.:.....|.| :|.
Human   303 EPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMI-----GLGGMAF-CSTLMTVSLLLKDNYNG 361

  Fly   363 LPLVLM-IIICYVA--NIGLIGIFFLVLVELFPVKIRSLATSLSVI--FLSLLVFGTLKLFPLML 422
            :..|.: .|:.:||  .||...|.:.::.|||....|..|.:::..  :.|..:.|.  |||...
Human   362 MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGL--LFPSAA 424

  Fly   423 HYWG----ISFTMWFSAASALLTFFYFWLF-LQETKGKSMIED 460
            ||.|    |.||      ..|:||..|..| :.||:|:: .||
Human   425 HYLGAYVFIIFT------GFLITFLAFTFFKVPETRGRT-FED 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	124/474 (26%)
		MFS_1	53..409	CDD:284993	99/387 (26%)
SLC2A3	NP_008862.1	MFS_GLUT_Class1	12..456	CDD:340989	127/483 (26%)
		Important for selectivity against fructose. /evidence=ECO:0000269|PubMed:26176916	277..279		0/1 (0%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:26176916	280..286		3/5 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143945
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.930