DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33282 and CG8249

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001246349.1	Gene:	CG8249 / 36742	FlyBaseID:	FBgn0034045	Length:	521	Species:	Drosophila melanogaster

Alignment Length:	478	Identity:	128/478 - (26%)
Similarity:	214/478 - (44%)	Gaps:	62/478 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RYQLLATVIVNIITFGHGVGVGWLSPTLTKIQTADSPLDFEVNLAQISWLGSMLGLDSLCGNLTI 79
            |.|::|.::.|:..|..|:.:.  .||.|..|..|:.....:|.:|.||..|:..|.:..|.|..
  Fly    43 RRQVIAVILANVGVFSTGMTLA--MPTATLHQLKDTTEPVHLNDSQASWFASVNALSAPIGGLLS 105

  Fly    80 AMLIERAGRKFCLYLMAGPYACIWILIYCAS----NVYY--LYAARFLCGFTGGAGYLVVP--IF 136
            ..|::|.|||..|.::.......|||:...|    |.::  |..:||:.|.  |.|....|  ::
  Fly   106 GFLLDRIGRKKSLIVLNVLIILAWILLATPSESDQNAFFWQLIVSRFMLGV--GMGLASAPPGVY 168

  Fly   137 ISEVADSNIRGALTSMVMLSVDLGIL----AGY--------ILSTYLAYHVVPFLAIILPVAYFI 189
            .:|::....||:|.....:||..||.    .||        |......|.:|..|. :||
  Fly   169 AAEISVPKTRGSLILGTSISVAGGITILYGIGYCIRDDFRLIALICCGYQLVALLC-VLP----- 227

  Fly   190 ANIMLPETAPYLLKKSQLAAAENSFRYYR--NQRSAICE-------QTSKVNFEELRTAVLSQQT 245
                |||:..:||.|.::..|:.|..|:|  |:...|..       |..:.:.::..|||.....
  Fly   228 ----LPESHCWLLSKKRVTEAKRSLNYFRGFNKSDEITHPQVLEEFQLLQKSLQQRNTAVKESFW 288

  Fly   246 RNA-TPLSYKDLTTKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSVVDVNTATIIIGL 309
            ||. .|..||.|....:|..|         .|.:|:|..|.:...|.:.:|..:|.....::|||
  Fly   289 RNLHEPEVYKPLVILMSLFAF---------QQLTGIFVVIVFAVQISQEAGIEIDPFMCAVLIGL 344

  Fly   310 VQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLA---KIYDLSDFNWLPLVLMIII 371
            .:::.......:::..|||...:|||:|:.:      |...||   :|..|.:..:||:|.::..
  Fly   345 ARLITTCPMGYILEWWGRRRAGIISTLGMSV------CMFLLAGHSQIEILKEVPYLPVVAIVGF 403

  Fly   372 CYVANIGLIGIFFLVLVELFPVKIRSLATSLSVIFLSLLVFGTLKLFPLMLHYWGISFTMWFSAA 436
            ..::.:||..:.|.::.||||.|:|..|:.|:|.....:.|..||.:|.:..|.|:|........
  Fly   404 IVLSTLGLYTLPFFMISELFPQKVRGPASGLTVAVGMFISFVVLKTYPGIKEYLGMSNCFIIFGV 468

  Fly   437 SALLTFFYFWLFLQETKGKSMIE 459
            .||....:.:|.|.||:.::::|
  Fly   469 MALFALIFVYLALPETRRRTLLE 491

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	120/459 (26%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	103/388 (27%)
CG8249	NP_001246349.1	MFS	49..479	CDD:119392	120/458 (26%)
CG8249	NP_001246349.1	Sugar_tr	60..496	CDD:278511	123/461 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444508
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	5	4.940