DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33282 and CG4607

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_572380.1	Gene:	CG4607 / 31653	FlyBaseID:	FBgn0029932	Length:	525	Species:	Drosophila melanogaster

Alignment Length:	484	Identity:	117/484 - (24%)
Similarity:	201/484 - (41%)	Gaps:	75/484 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QLLATVIVNIITFGHGVGVGWLSPTLTKIQTADSPLDFEVNLAQISWLGSMLGLDSLCGNLTIAM 81
            |.|...:.|....|.|:.|.  .|.:|..|..|....|.:|..:.||..|:..:....|.|.::.
  Fly    45 QELMVFLGNSGVLGSGMVVS--MPAVTLNQLHDETQPFWLNKDESSWFASIQNMACPLGGLLVSY 107

  Fly    82 LIERAGRKFCLYL-----MAGPYACIWILIYCA------SNVYY-LYAARFLCGFTGGAGYLVVP 134
            .::|.|||..:.|     :.|     |||:..:      ..:|| :...|...|...|.....|.
  Fly   108 FLDRIGRKHTILLTNLIGLIG-----WILLVTSFMHSDRDMIYYQMLLGRCFGGIMIGMFVSPVG 167

  Fly   135 IFISEVADSNIRGALTSMVMLSVDLGILAGYILSTYLAYHVVPFLAIILPVA--YFIANIML--- 194
            ::.:|::...|||.|    :|...||:.:|.:|...|.|.:...:.:|..::  |.:|..:|
  Fly   168 VYSAEISLPKIRGRL----ILGTSLGLASGILLMYCLGYFIRHNIQLIFGISCCYQLAATLLVFP 228

  Fly   195 -PETAPYLLKKSQLAAAENSFRYYRNQRSAICE-----QTSKVNFEELRTA--------VLSQQT 245
             ||:..:||.:.:...|..|.||:|.......:     :....:.:||..|        .|||..
  Fly   229 MPESPSWLLTRGKEERARKSLRYFRGLPKKEVDYVPEFEAELAHMKELADASNTTAAGESLSQMI 293

  Fly   246 RNATPLSYKDLTTKPALKGFAASIVLSLGYQFSGVFSFINYMSDIFKASGSVVDVNTATIIIGLV 310
            ..  |..||.:.......||         .|..||...|.|...|.:.:|..:|.....:::|:.
  Fly   294 HR--PEVYKPVLMMTTFFGF---------QQACGVVVIIVYAVQIAQQAGVTIDPVLVAVMLGVA 347

  Fly   311 QIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLAKIYDLSDFNWLPLVL-----MII 370
            :|:.....:.:.:..||:...:.|..|:|      .|...||      ..||.|..|     :.:
  Fly   348 RIITTLFMSGIFEKWGRKPSGIFSATGMG------ACMLLLA------GGNWFPDTLGTLHWLPV 400

  Fly   371 ICYVANI-----GLIGIFFLVLVELFPVKIRSLATSLSVIFLSLLVFGTLKLFPLMLHYWGISFT 430
            .|.||:|     |::.:.|.::.|:||.:.|..|:.:::.|..:|.|..||::|.|....|.:..
  Fly   401 ACIVAHIVFSTMGMLTLPFFMISEVFPQRARGSASGIAIFFGMILAFIMLKIYPNMEAALGTANL 465

  Fly   431 MWFSAASALLTFFYFWLFLQETKGKSMIE 459
            ..|.|..:.|...:..:|:.||:|:::.|
  Fly   466 FAFYAGISFLAAAFIGVFVPETRGRTLEE 494

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	110/467 (24%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	92/396 (23%)
CG4607	NP_572380.1	MFS	55..484	CDD:119392	109/462 (24%)
CG4607	NP_572380.1	SP	67..495	CDD:273317	110/460 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444509
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940