DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33282 and Y37A1A.3

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_502675.4	Gene:	Y37A1A.3 / 189599	WormBaseID:	WBGene00012536	Length:	500	Species:	Caenorhabditis elegans

Alignment Length:	528	Identity:	105/528 - (19%)
Similarity:	201/528 - (38%)	Gaps:	144/528 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 RYQLLATVIVNIITFGHGVGVGWLSPT-------LTKIQTADSPLDFEVNLAQISW--LGSMLGL 70
            |..|:|.::....:|..|..:...:|.       |...:.:::|.|.|::..:..|  :.::..|
Worm    23 RTSLMAIIVAFGSSFSFGFQLLITNPAQGAFIKFLNASKHSNNPDDNELSHLENEWSFIVAIFFL 87

  Fly    71 DSLCGNLTIAMLIERAGRK----FCLYLMAGPYACIWILIYCASNVYYLYAARFLCGFTGGAGYL 131
            .|..|...|..:.||.|||    ..|:..........:..:..:::.::: ||||.|........
Worm    88 GSATGAFLIKTVAERFGRKKGVIVSLFAQVTSSMLTIVSFWIVNHILFIF-ARFLMGVGITISMG 151

  Fly   132 VVPIFISEVADSNIRGALTSMVMLSVDLGILAGYILS-------------TYLAYHVV-PFLAII 182
            :..:|::|.:.:..||..:.:..:.:.|.|..|.:::             .||...:: ..:.:|
Worm   152 IAAMFVTESSPAYCRGVSSLINGVLLQLSITVGAVMAMPNVLGNETHWWYLYLFQLIINTTVLVI 216

  Fly   183 LPVAY----FIANIMLPETAPYLLKKSQLAAAENSFRYYRNQRSAICEQTSKV---NFEELRTAV 240
            ||..:    ::|:..:.....:.:.|:::.|   |.::|.    .|.:..::|   |..|.....
Worm   217 LPWVHESPSYLASQDIKHHELHAMFKAKIVA---SVKFYH----GISDPEAEVFADNLIETHQIT 274

  Fly   241 LSQQT----------RNATPLSYKDLTTKPALKG------FAASIVLSLGYQFSGVFSFINYMSD 289
            .||::          |..|.|... :|...|:.|      ||..|::::|
Worm   275 RSQESIISVWKSPFNRRGTLLGMM-VTFSMAMSGITVINAFAFEILMNVG--------------- 323

  Fly   290 IFKASGSVVDVNTATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLAKI 354
             .|...:.:    |...|......|:..||.::|..|||.| ||||    .||:|......:..:
Worm   324 -MKQDTAAI----ANAAICFFSFAGILVSTKIIDHFGRRPL-LIST----FGCLAVVNVVIVGLM 378

  Fly   355 YDLSD----------------FNWL------PLVLMII------ICYVA-----NIGLIGIFFLV 386
            |..::                ||:|      ||.:.|.      .|..|     |..:..:.||:
Worm   379 YTFAETQNQIVSYFLISAICMFNFLFAMGPGPLSMFITGELVPQNCRSASSVWTNAVMAVVRFLI 443

  Fly   387 LVELFPVKIRSLATSLSVIFLSLLVFGTLKLFPLMLHYWGISFTMWFSAASALLTFFYFWLFLQE 451
            |....|||      :::..|::..:|..:   |:::               |:|..|:   .|.|
Worm   444 LTFYLPVK------NMTSEFMAYAIFFVV---PMIV---------------AVLVIFF---LLPE 481

  Fly   452 TKGKSMIE 459
            |||:::.|
Worm   482 TKGRNVEE 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	96/509 (19%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	86/431 (20%)
Y37A1A.3	NP_502675.4	MFS_GLUT_Class1_2_like	28..485	CDD:340915	101/517 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157977
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940