DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33282 and Slc2a9

DIOPT Version :9

Sequence 1:	NP_001097067.1	Gene:	CG33282 / 2768939	FlyBaseID:	FBgn0053282	Length:	460	Species:	Drosophila melanogaster
Sequence 2:	NP_001095884.1	Gene:	Slc2a9 / 117591	MGIID:	2152844	Length:	538	Species:	Mus musculus

Alignment Length:	490	Identity:	122/490 - (24%)
Similarity:	218/490 - (44%)	Gaps:	67/490 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 QQKTRYQLLATVIVNII-TFGHGVGVGW-LS----PTL--------TKIQTADSPLDFEVNLAQI 61
            |::|:....:.|:..:: .||.....|: ||    ||.        |..:....|:|.:......
Mouse    27 QRRTKKWSFSLVVAALVGAFGSSFLYGYNLSVVNAPTPYIKAFYNGTWYRRHGQPIDPDTLTLLW 91

  Fly    62 SWLGSMLGLDSLCGNLTIAMLIERAGRKFCLYLMAGPYACIWILIYC---ASNVYYLYAARFLCG 123
            |...|:..:..|.|.|.:.|:.:..|||..|.:..|......:|:.|   |.....|...||:.|
Mouse    92 SVTVSIFAIGGLVGTLMVKMIGKFLGRKSTLLVNNGFAISAALLMACSLRAGTFEMLIVGRFIMG 156

  Fly   124 FTGGAGYLVVPIFISEVADSNIRGALTSMVMLSVDLGILAGYIL---------STYLAYHVVPFL 179
            ..||.....:|::::|::...|||:|..:..:.:.:|:.:|.:|         ||:      |:|
Mouse   157 VDGGIALSALPMYLNEISPKEIRGSLGQVTAIFICIGVFSGQLLGLPELLGRESTW------PYL 215

  Fly   180 --AIILPVAYFIANI-MLPETAPYLL-KKSQLAAAENSFRYYRNQRSAICEQTSKVNFEELRTAV 240
              .||:|....:|:: .|||:..||| :|...|.|..:|:.:..:...         .:||..|:
Mouse   216 FGVIIVPALVQLASLPFLPESPRYLLFEKHDEAGAMKAFQTFLGKADV---------SQELEEAL 271

  Fly   241 L-SQQTRNATPLSYKDLTTKPALKGFAASIVLSL-GYQFSGVFSFINYMSDIFKASGSVVD-VNT 302
            . |:..||...:|..:|...|.::....:::::: .||..|:.:...|.:.||..:|...| :..
Mouse   272 AESRVQRNLRLVSVLELLRAPFVRWQVITVIITMASYQLCGLNAIWFYTNSIFGKAGIPQDKIPY 336

  Fly   303 ATIIIGLVQIVGVYTSTILVDIVGRRVLMLISTMGVGIGCIAFGCFTYLAKIYDLSDFNWLPLVL 367
            .|:..|.::.:....|.::::.:|||.|::   .|.|:..:.||..|....:.|.:.  |:|  .
Mouse   337 ITLSTGGIETLAAIFSGLVIERLGRRPLLI---GGFGLMALFFGTLTATLTLQDQAP--WVP--Y 394

  Fly   368 MIIICYVANI-----GLIGIFFLVLVELFPVKIRSLATSL--SVIFLSLLVFGTLKLFP-LMLHY 424
            :.|:|.:|.|     |..||.|::..|.|....|..|..:  :|.:||....|.  ||| :....
Mouse   395 LSIVCILAIIASFCSGPGGIPFILTGEFFQQSERPAAFMIAGTVNWLSNFAVGL--LFPFIQKSL 457

  Fly   425 WGISFTMWFSAASALLTFFYFWLFLQETKGKSMIE 459
            ....|.::.:...|..|:|||  .|.|||.::..|
Mouse   458 DSYCFLVFATICIAGATYFYF--VLPETKNRTHAE 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33282	NP_001097067.1	MFS	21..448	CDD:119392	115/467 (25%)
CG33282	NP_001097067.1	MFS_1	53..409	CDD:284993	94/381 (25%)
Slc2a9	NP_001095884.1	MFS_GLUT_Class2	40..491	CDD:340990	119/477 (25%)
Slc2a9	NP_001095884.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	495..538
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.930