DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and HXT5

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_011964.1	Gene:	HXT5 / 856496	SGDID:	S000001138	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	498	Identity:	123/498 - (24%)
Similarity:	212/498 - (42%)	Gaps:	81/498 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LAAISVNIISISYGAFC-GWPS---------SSFLELSSENSPLDTGPLTPTDQGWVASNICLGG 66
            |..:||..:.:::|.|. ||.:         :.|:..........|..|:....|.:.|...:|.
Yeast    83 LLFVSVCCLMVAFGGFVFGWDTGTISGFVRQTDFIRRFGSTRANGTTYLSDVRTGLMVSIFNIGC 147

  Fly    67 LVGTFLFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTP--MHLIIARFIGGAAGGGCFTVIPI 129
            .:|..:.:.|.|..|||:.||.:.:...:| :||..|...  ....|.|.|.|...||...:.|:
Yeast   148 AIGGIVLSKLGDMYGRKIGLMTVVVIYSIG-IIIQIASIDKWYQYFIGRIISGLGVGGITVLAPM 211

  Fly   130 YIAELASDNIRGILGVFLVLTCNFGLVLAFVLGY----YFNYAQ--------VSWIVSSLSFVFV 182
            .|:|::...:||.|.....|...||:.|.:...:    |.|..|        .:|.:    |:.|
Yeast   212 LISEVSPKQLRGTLVSCYQLMITFGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWSI----FMIV 272

  Fly   183 GCFWFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDD 247
            | ..|:||:|::|.::.|||||:.||     .::|...|.|..:.||::..:::       ::.:
Yeast   273 G-MTFVPESPRYLVEVGKIEEAKRSL-----ARANKTTEDSPLVTLEMENYQSS-------IEAE 324

  Fly   248 DAATGVTWSDFAEGKTR--KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVG 310
            ..|...:|.:...||.:  :..|:|:.:.|..||.|......|...||:..|.. .....||::|
Yeast   325 RLAGSASWGELVTGKPQMFRRTLMGMMIQSLQQLTGDNYFFYYGTTIFQAVGLE-DSFETAIVLG 388

  Fly   311 VIQLMGTYASTVLVERLGRKILLLVSAVG----------IGL------GQ---SAMGTYSYFQML 356
            |:..:.|:.|...|:|.||:..||...||          :|:      ||   |:.|..:...:.
Yeast   389 VVNFVSTFFSLYTVDRFGRRNCLLWGCVGMICCYVVYASVGVTRLWPNGQDQPSSKGAGNCMIVF 453

  Fly   357 GCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLM 421
            .|              |.:|..|.....:.::::||..|.::|..|:.|..:..|:.........
Yeast   454 AC--------------FYIFCFATTWAPVAYVLISESYPLRVRGKAMSIASACNWIWGFLISFFT 504

  Fly   422 PVFTESLGM-HGTVFMFASLSFLAAIFIAIFVPETKGKSVDAI 463
            |..|.::.. :|.|||  .....|..::..|||||||.:::.:
Yeast   505 PFITSAINFYYGYVFM--GCMVFAYFYVFFFVPETKGLTLEEV 545

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	107/437 (24%)
HXT5	NP_011964.1	Sugar_tr	89..549	CDD:395036	120/492 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342502
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740