DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and HXT2

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_013724.1	Gene:	HXT2 / 855023	SGDID:	S000004613	Length:	541	Species:	Saccharomyces cerevisiae

Alignment Length:	507	Identity:	119/507 - (23%)
Similarity:	197/507 - (38%)	Gaps:	115/507 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 ISISYGAFC-GWPSSSFLELSSENSPLDTGPLT---------------PTDQGWVASNICLGGLV 68
            :.|::|.|. ||               |||.::               .:|..:..|::..|.:|
Yeast    61 LMIAFGGFVFGW---------------DTGTISGFVNQTDFKRRFGQMKSDGTYYLSDVRTGLIV 110

  Fly    69 GTF---------LFTWLADRIGRKLCLMWMALPNLLGWVIIPFARTP--MHLIIARFIGGAAGGG 122
            |.|         ....|.|..||::.||.:.|..::| ::|..|.:.  ....|.|.|.|...||
Yeast   111 GIFNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVG-IVIQIASSDKWYQYFIGRIISGMGVGG 174

  Fly   123 CFTVIPIYIAELASDNIRGILGVFLVLTCNFGLVLAFVLGYYFNYA------QVSWIVS-SLSFV 180
            ...:.|..|:|.|..:|||....|..|....|:    .|||..||.      .|.|.|. .|:|.
Yeast   175 IAVLSPTLISETAPKHIRGTCVSFYQLMITLGI----FLGYCTNYGTKDYSNSVQWRVPLGLNFA 235

  Fly   181 F----VGCFWFMPETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTA 241
            |    :.....:||:|:.|.:..:.|:|:.||     .|||       ::.:|...:.....|..
Yeast   236 FAIFMIAGMLMVPESPRFLVEKGRYEDAKRSL-----AKSN-------KVTIEDPSIVAEMDTIM 288

  Fly   242 DGVDDDDAATGVTWSDF--AEGKTRKAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTV 304
            ..|:.:..|...:|.:.  .:|......::|:.:.|..||.|......|...||...|.. ....
Yeast   289 ANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVGMK-DSFQ 352

  Fly   305 AAIIVGVIQLMGTYASTVLVERLGRKILLL------------VSAVGI------GLGQ----SAM 347
            .:|::|::....|:.:...|::.||:..||            .|.||:      |..|    :|.
Yeast   353 TSIVLGIVNFASTFVALYTVDKFGRRKCLLGGSASMAICFVIFSTVGVTSLYPNGKDQPSSKAAG 417

  Fly   348 GTYSYFQMLGCPVASFSWVPIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWL 412
            .....|..|.....:.||.|||                 :::|:|..|.::::.|:.|.:...|:
Yeast   418 NVMIVFTCLFIFFFAISWAPIA-----------------YVIVAESYPLRVKNRAMAIAVGANWI 465

  Fly   413 ISTCAVKLMPVFTESLGM-HGTVFMFASLSFLAAIFIAIFVPETKGKSVDAI 463
            .........|..|.::|. :|.||| ..|.| :..::..||.||||.:::.:
Yeast   466 WGFLIGFFTPFITSAIGFSYGYVFM-GCLVF-SFFYVFFFVCETKGLTLEEV 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	105/463 (23%)
HXT2	NP_013724.1	Sugar_tr	59..519	CDD:395036	119/507 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342500
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740