DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and HXT11

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_014486.1	Gene:	HXT11 / 854009	SGDID:	S000005516	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	488	Identity:	122/488 - (25%)
Similarity:	207/488 - (42%)	Gaps:	65/488 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 ISVNIISISYGAFC-GWPS---SSFLELS------SENSPLDTGPLTPTDQGWVASNICLGGLVG 69
            :::..:.|::|.|. ||.:   |.|:.||      .:.:...|..|:....|.:.|...:|..:|
Yeast    61 VAILCLMIAFGGFIFGWDTGTISGFVNLSDFIRRFGQKNDKGTYYLSKVRMGLIVSIFNIGCAIG 125

  Fly    70 TFLFTWLADRIGRKLCLMWMALPNLLGWVI-IPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAE 133
            ..:.:.:.|..||::.|:.:....::|.:| |..........|.|.|.|...||...:.|:.|:|
Yeast   126 GIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKWYQYFIGRIISGLGVGGIAVLSPMLISE 190

  Fly   134 LASDNIRGILGVFLVLTCNFGLVLAFVLGY----YFNYAQVSWIVS-SLSFVF----VGCFWFMP 189
            :|..:|||.|.....|....|:.|.:...|    |.|..|  |.|. .|.|.:    |....|:|
Yeast   191 VAPKHIRGTLVQLYQLMGTMGIFLGYCTNYGTKNYHNATQ--WRVGLGLCFAWATFMVSGMMFVP 253

  Fly   190 ETPQHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVT 254
            |:|::|.::.|.|||:.||.     |||........|.:|...:|.       |::.:..|...:
Yeast   254 ESPRYLIEVGKDEEAKRSLS-----KSNKVSVDDPALLVEYDTIKA-------GIELEKLAGNAS 306

  Fly   255 WSDFAEGKTR--KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGT 317
            ||:....||:  :..|:|:.:.|..||.|......|...||:..|.. .....:||:||:....:
Yeast   307 WSELLSTKTKVFQRVLMGVMIQSLQQLTGDNYFFYYGTTIFKSVGLK-DSFQTSIIIGVVNFFSS 370

  Fly   318 YASTVLVERLGRKILLLVSAVGIGLGQSAMGTYSYFQMLGCPVASFSW----------------V 366
            :.:...:||.||:..||..|.      |.:..::.|..:|   .:..|                .
Yeast   371 FIAVYTIERFGRRTCLLWGAA------SMLCCFAVFASVG---VTKLWPQGSSHQDITSQGAGNC 426

  Fly   367 PIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGM- 430
            .|....|.:|..|.......:::|||..|.:::|..:.|..:..|:.........|..|.::..
Yeast   427 MIVFTMFFIFSFATTWAGGCYVIVSETFPLRVKSRGMAIATAANWMWGFLISFFTPFITGAINFY 491

  Fly   431 HGTVFMFASLSFLAAIFIAIFVPETKGKSVDAI 463
            :|.||: ..|.| |..::..|||||||.:::.:
Yeast   492 YGYVFL-GCLVF-AYFYVFFFVPETKGLTLEEV 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	105/430 (24%)
HXT11	NP_014486.1	Sugar_tr	64..526	CDD:395036	122/485 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342509
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740