DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33281 and HXT16

DIOPT Version :9

Sequence 1:	NP_995620.1	Gene:	CG33281 / 2768938	FlyBaseID:	FBgn0053281	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_012692.3	Gene:	HXT16 / 853623	SGDID:	S000003919	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	488	Identity:	119/488 - (24%)
Similarity:	205/488 - (42%)	Gaps:	84/488 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ISYGAFC-GWPS---SSFLELSSENSPLDTGPLTPTDQGWVASNICLGGLVGTF---------LF 73
            :|:|.|. ||.|   :.|:.:  :|..::.|....:...:..||:.:|.||..|         .|
Yeast    67 VSFGGFLPGWDSGITAGFINM--DNFKMNFGSYKHSTGEYYLSNVRMGLLVAMFSVGCSIGGVAF 129

  Fly    74 TWLADRIGRKLCLMWMALPNLLGWVI-IPFARTPMHLIIARFIGGAAGGGCFTVIPIYIAELASD 137
            ..|||.:||:|.::.:.|..::|.:| |..........:.:.|.|...|||..:.|:.::|:|..
Yeast   130 ARLADTLGRRLAIVIVVLVYMVGAIIQISSNHKWYQYFVGKIIYGLGAGGCSVLCPMLLSEIAPT 194

  Fly   138 NIRGILGVFLVLTCNFGLVLAFVLGY----YFNYAQVSW-IVSSLSF-----VFVGCFWFMPETP 192
            ::||.|.....|...||:.|.:...|    |.|.||  | |...|.|     :.||.. .:||:|
Yeast   195 DLRGGLVSLYQLNMTFGIFLGYCSVYGTRKYSNTAQ--WRIPVGLCFLWALIIIVGML-LVPESP 256

  Fly   193 QHLAKINKIEEAEHSLRYYRNIKSNPAKELSEELQLELQKLKTTEKTTADGVDDDDAATGVTWSD 257
            ::|.:..:.|||..|:.....:.......|.:..::....|...|...|            :|.:
Yeast   257 RYLIECERHEEACVSIAKIDKVSPEDPWVLKQADEINAGVLAQRELGEA------------SWKE 309

  Fly   258 FAEGKTR--KAFLIGLGLISFNQLCGCFAMLNYTAVIFEQAGSSLPPTVAAIIVGVIQLMGTYAS 320
            ....||:  :..:.|:.:.:|.||.|......|...||:..|.: .....:|::|.:....|..:
Yeast   310 LFSVKTKVLQRLITGILVQTFLQLTGENYFFFYGTTIFKSVGLT-DGFETSIVLGTVNFFSTIIA 373

  Fly   321 TVLVERLGRKILLLVSA----------VGIGL---------GQSAMGTYSYFQMLGCPVASFSWV 366
            .::|:::||:..||..|          ..||:         |.|:.|..:...:..|
Yeast   374 VMVVDKIGRRKCLLFGAASMMACMVIFASIGVKCLYPHGQDGPSSKGAGNAMIVFTC-------- 430

  Fly   367 PIAGFSFMLFLAAVGLLSLPFLVVSEIMPQKIRSTAIMILMSTLWLISTCAVKLMPVFTESLGM- 430
                  |.:|..|.....:.::||:|..|.|::|.|:.|..:..||.........|..|.|:..
Yeast   431 ------FYIFCFATTWAPVAYIVVAESFPSKVKSKAMSISTAFNWLWQFLIGFFTPFITGSIHFY 489

  Fly   431 HGTVFMFASLSFLAAIFIAI--FVPETKGKSVD 461
            :|.||    :..|.|:|:.:  |:|||.|.|::
Yeast   490 YGYVF----VGCLVAMFLYVFFFLPETIGLSLE 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33281	NP_995620.1	MFS	50..452	CDD:119392	104/445 (23%)
HXT16	NP_012692.3	Sugar_tr	63..524	CDD:278511	119/488 (24%)
HXT16	NP_012692.3	MFS	67..510	CDD:119392	114/478 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342503
Domainoid	1	1.000	165	1.000	Domainoid score	I819
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740